摘要
采用液质联用法检测钩吻根、茎、叶、花中11种生物碱含量。结果表明:4个部位钩吻生物碱含量从高到低依次为根>叶>花>茎;从根的钩吻生物碱含量来看,11种生物碱的检出量从高到低依次为钩吻素甲>钩吻素子>钩吻绿碱>钩吻素己>胡蔓藤碱丁>胡蔓藤碱乙>(Z)-阿枯米定碱>钩吻素戊>N-甲氧基无水老刺木碱二醇>兰金断肠草碱>常绿钩吻碱。综上所述,钩吻根部是获取生物碱的最佳提取部位,钩吻素甲、钩吻素子和钩吻素己可能是其主要的药理和毒性活性成分。
The contents of 11 alkaloids in the root,stem,leaf and flower of Gelsemium elegans were determined by HPLC-MS.The results showed that the order of alkaloid content in four parts was root>leaf>flower>stem.In terms of the alkaloids content in the root,the detected amounts of 11 alkaloids were as follows:gelsemine>koumine>gelsevirine>gelsenicine>humantenirine>humantenine>19-(Z)-akuammidine>koumidine>N-methoxyanhydrovobasinediol>rankini-dine>sempervirine.In conclusion,the root of Gelsemium elegans was the best site to exact alkaloids.Gelsemine,koumine and gelsenicine may be the main pharmacological and toxic active components.
作者
陈超杰
叶美麟
覃妮凤
康宸毓
江政
黄蘅
罗达龙
CHEN Chaojie;YE Meilin;QIN Nifeng;KANG Chenyu;JIANG Zheng;HUANG Heng;LUO Dalong(School of Food and Pharmaceutical Engineering,Wuzhou University,Wuzhou Guangxi 543002;Wuzhou Food and Drug Inspection Institute,Wuzhou Guangxi 543002)
出处
《现代农业科技》
2022年第19期178-181,共4页
Modern Agricultural Science and Technology
基金
国家自然科学基金项目(81860736)
广西高校大学生创新创业训练计划项目(202011354096,202011354024)。
关键词
钩吻
生物碱
分析
活性成分
Gelsemium elegans
alkaloid
analysis
active ingredient
