基于“风邪犯肺”运用自拟祛风止咳汤加减治疗感冒后咳嗽的疗效观察

Therapeutic effects of dialectical addition and subtraction treatment based on self-made Qufeng Zhike Decoction on cough caused by wind dryness invading the lung

目的探讨基于“风邪犯肺”运用自拟祛风止咳汤加减治疗感冒后咳嗽的疗效。方法选择2021年5月至2022年4月淮南市中医院就诊的感冒后咳嗽患者30例。患者首诊予自拟祛风止咳汤加减,水煎服(代赭石先煎30 min,旋复花包煎)或中药颗粒剂型开水冲服,每天1剂,连服5剂。复诊时根据咳嗽改善情况加减药方。5 d为1个疗程,一般予2~3个疗程。观察疗效和不良反应以及比较治疗前、治疗后15 d咳嗽症状(咳嗽、咳痰、咽痒)积分变化。结果30例患者均积极配合治疗。30例患者显效19例,有效9例,无效2例,总有效率为93.33%(28/30)。30例患者有2例诉轻微胃部不适(改为餐后1 h服药后缓解),余未见明显不良反应。患者治疗后咳嗽、咳痰、咽痒症状积分较治疗前均明显改善[(2.38±0.51)分比(1.00±0.85)分,(0.88±0.54)分比(0.29±0.08)分,(0.98±0.67)分比(0.65±0.33)分,t=2.36、2.98、2.01,均P<0.05]。结论基于“风邪犯肺”理论运用自拟祛风止咳汤加减治疗感冒后咳嗽,疗效满意,无明显不良反应,患者依从性高。

Objective To investigate the therapeutic effects of dialectical addition and subtraction treatment based on self-made Qufeng Zhike Decoction on cough caused by wind dryness invading the lung.Methods Thirty patients with cough after catching a cold who were admitted by Huainan Hospital of Traditional Chinese Medicine from May 2021 to May 2022 were included in this study.These patients were treated with self-made Qufeng Zhike Decoction(first decocting the ochre for 30 minutes,then decocting inula flower in cloth bags,or traditional Chinese medicine drug granules for drinking with boiled warm water),1 dose per day,5 doses in total at first diagnosis.During the follow-up visit,patients were given an dialectical addition and subtraction treatment according to the improvement of cough.Five days of dialectical addition and subtraction treatment were taken as one course of treatment,and two or three courses of treatment were used.Therapeutic effects and adverse reactions were recorded.Scores of cough,expectoration and pharyngeal itching before and 15 days after treatment were recorded.Results All 30 patients actively cooperated with the treatment.Among 30 patients,treatment was remarkably effective in 19 patients,effective in 9 patients,and ineffective in 2 patients,with a total response rate of 93.33%(28/30).Among 30 patients,two complained of mild stomach discomfort(relieved after taking medicine 1 hour after a meal).No obvious adverse reactions were found in the remaining patients.Compared with before treatment,scores of cough,expectoration and pharyngeal itching were significantly decreased after treatment[cough:(2.38±0.51)points vs.(1.00±0.85)points;expectoration:(0.88±0.54)points vs.(0.29±0.08)points;pharyngeal itching:(0.98±0.67)points vs.(0.65±0.33)points,t=2.36,2.98,2.01,all P<0.05].Conclusion Dialectical addition and subtraction treatment based on self-made Qufeng Zhike Decoction for treatment of cough caused by wind dryness invading the lung has a promising curative effect,without obvious adverse reactions.