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动物基因编辑的若干伦理问题及其治理 被引量:1

Ethical Issues and Its Governance in Animal Gene Editing
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摘要 我国学界对人类基因编辑的伦理问题研究较多,而对动物基因编辑的伦理问题缺乏应有的关注。目前人们已经在农业和医学领域对动物进行基因编辑,在其他领域也有动物基因编辑的尝试。进行动物基因编辑可以带来许多利益。例如,在农业领域,对动物进行基因编辑可以提高其肉、奶、毛的产量和品质,或提高动物的抗病性;在医学领域,对实验动物进行基因编辑可以制备疾病动物模型,或培养供人类移植的备份器官。此外,科学家还可以通过基因编辑来定制宠物,或提升工作动物的功能,或提高指标动物对环境的敏感性,等等。但是,动物基因编辑也带来许多伦理问题,从非人类中心主义视角看,动物基因编辑关乎动物福利和动物权利等伦理问题;从人类中心主义视角看,动物基因编辑关系到人类福祉和个人权利问题,其中包括食品安全、经济效益、知情权利、分配公正、物种多样性、环境保护、生态平衡等伦理问题。因此,人们在进行动物基因编辑时应制定或遵循相应的伦理原则,并采取恰当的治理措施。 There are many studies on the ethical issues of human gene editing in Chinese academic circles, but there is a lack of due attention to the ethical issues of animal gene editing. At present, people have had animal genes editing in the fields of agriculture and medicine, and there are also attempts in other fields. Animal gene editing can bring many benefits. For example, gene editing of farm animals in the agricultural field can increase the yield and quality of meat, milk and fur of animals by genetic breeding, or improve the disease resistance of animals. Gene editing of experimental animals in the medical field can prepare experimental animal models of diseases, or cultivate backup organs for human transplantation. In addition, pets can also be customized by gene editing, and the functions of working animals can be improved, the sensitivity of indicator animals to the environment can be improved by animal gene editing. However, animal gene editing also brings a series of ethical issues. From the perspective of non-anthropocentrism, animal gene editing is related to ethical issues such as animal welfare and animal rights;From the perspective of anthropocentrism, animal gene editing is related to human well-being and individual rights, including food safety, economic benefits, the right of informed consent, justice of distribution, species diversity, environmental protection, ecological balance and other ethical issues. Therefore, people should formulate or follow corresponding ethical principles and take appropriate governance measures when conducting to animal gene editing.
作者 程新宇 CHENG Xin-yu(HUST)
出处 《华中科技大学学报(社会科学版)》 CSSCI 北大核心 2022年第5期9-16,共8页 Journal of Huazhong University of Science and Technology(Social Science Edition)
基金 国家社会科学基金项目“责任伦理视角下基因编辑问题研究”(22BZX092) 华中科技大学人权法律研究院专项课题资助(2022WKFZZX009) 华中科技大学文科双一流建设项目基金资助“科技伦理与‘哲学+’前沿创新团队”。
关键词 动物基因编辑 动物福利 人类福祉 生态环境 animal gene editing animal welfare human well-being ecological environment
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  • 1张然,徐慰倬,孔平,许红韬,李宁.转基因动物应用的研究现状与发展前景[J].中国生物工程杂志,2005,25(8):16-24. 被引量:15
  • 2陈广,陈景武.Logistic回归分析的判别预测功能及其应用[J].数理医药学杂志,2007,20(3):280-281. 被引量:16
  • 3Gordon J W, Scangos G A, Plotkin D J, et al. Genetic transformation of mouse embryos by microinjection of purified DNA[ J]. Proc Natl Aead Sci USA,1980,77(12) :7380-7384.
  • 4Wilmut I, Schnieckle A E, Mc Whir J, et al. Viable offspring derived from fetal and adult mammalian cells [ J]. Cloning and Stem Cells,2007,9( 1 ) :3-7.
  • 5Cibelli J B,Stice S L,Golueke P J,et al. Cloned transgeniccalves produced from nonquiescent fetal flbroblasts[ J ]. Science, 1998, 280(5367) :1256-1258.
  • 6Park K W, Cheong H T, Lai L, et al. Production of nuclear transfer-derived swine that express the enhanced green fluorescent protein [ J ]. Anita Biotechnol, 2001,12 ( 2 ) : 173 - 181.
  • 7Wolf E, Schernthaner W, Zakhartchenko V, et al. Brem G. Transgenic technology in farm animals progress and perspectives [ J ]. ExpPhysiol, 2000,85 ( 6 ) : 615-625.
  • 8Michael Balls. The increasing use of genetically-altered animals threatens the credibility of directive 2010/63/EU [ S ]. ATLA41, 2013 : 199-203.
  • 9Adams D J, Biggs P J, Cox J, et al. Mutagenic in sertion and chromosome engineering resource( MICER ) [ J]. Nature Genet, 2004,36:867-871.
  • 10Generation of PPAR7 mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning[J].Cell Research,2011,21(6):979-982. 被引量:47

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