妊娠期高脂血症与妊娠结局的研究进展

Research progress of hyperlipidemia in pregnancy and pregnancy outcome

妊娠期高脂血症是目前产科中急需引起重视及提早预防管理的疾病,其中病理性高脂血症极易导致母婴近、远期并发症,严重危及胎儿质量及导致产妇二次妊娠再发血脂代谢紊乱,其病因复杂,至今作用机制尚未被完全阐明。妊娠期高脂血症在临床较为常见,逐渐引起临床工作者的重视,近年来我国妊娠期血脂异常产妇的知晓率和治疗率虽有提高,但仍处于较低水平,控制孕期血脂异常的工作仍待加强。因此,本文结合国内外妊娠期高脂血症的研究现状,着重对妊娠期高脂血症对妊娠结局的影响加以综述,并对妊娠期病理性高脂血症的临床研究前景进行展望。

Hyperlipidemia in pregnancy is a disease that urgently needs attention and early prevention and management in obstetrics at present,in which pathological hyperlipidemia can extremely be easy to cause short-term and long-term complications of mother and infants,seriously endangering fetal quality and easily leading to recurrent dyslipidemia in the second pregnancy of parturient.Its etiology is complex,and its mechanism of action has not yet been fully elucidated.Hyperlipidemia in pregnancy is relatively common in clinic,which has gradually attracted the attention of clinical workers.Although the awareness rate and treatment rate of parturient with dyslipidemia in China have improved in recent years,they are still at a relatively low level,and the control of dyslipidemia in pregnancy still needs to be strengthened.Therefore,combined with the status quo of research on hyperlipidemia in pregnancy at home and abroad,the impact of hyperlipidemia in pregnancy on the pregnancy outcome is reviewed and focused on in this paper,and the clinical research prospect of pathological hyperlipidemia in pregnancy is forecasted.