慢性阻塞性肺疾病并发弥散性血管内凝血1例报道

A case report of COPD complicated by disseminated intravascular coagulation

慢性阻塞性肺疾病(简称慢阻肺)是一种严重危害人类健康的常见病,其特征是持续存在的气流受限和相应的呼吸系统症状。由于反复存在的慢性炎症、低氧血症、高碳酸血症等因素,慢阻肺患者往往存在血液高凝状态,甚至发生弥散性血管内凝血(DIC),严重者危及生命。现报道1例慢阻肺并发DIC患者的诊治过程,并进行相关文献复习,以提高临床医师对慢阻肺患者高凝状态的认识。同时探讨并发弥散性血管内凝血的预防策略,以减少发病率。

Chronic obstructive pulmonary disease(COPD)is a common disease that seriously endangers human health and is characterized by persistent airflow limitation and corresponding respiratory symptoms.Due to recurrent chronic inflammation,hypoxemia,hypercapnia and other factors,patients with COPD often suffer from blood hypercoagulability and even disseminated intravascular coagulation(DIC),which can be lifethreatening in severe conditions.This paper herein reports the diagnosis and treatment process of a patient with COPD complicated by DIC and reviews the relevant literature in order to improve clinicians’awareness of the hypercoagulability in patients with COPD.Besides,it discusses how to prevent concomitant DIC and reduce its morbidity.