中药超声雾化熏蒸联合睑板腺按摩对睑板腺功能障碍的疗效评价

Efficacy evaluation of TCM medicine ultrasonic atomization fumigation combined with meibomian gland massage on meibomian gland dysfunction

目的:评价中药超声雾化熏蒸联合睑板腺按摩治疗睑板腺功能障碍(Meibomian Gland Dysfunction,MGD)的疗效。方法:选取2019年9月-2020年9月在眉山市中医医院就诊的280例MGD患者,随机分为研究组和对照组,两组患者均行基础治疗,对照组在基础治疗上行睑板腺按摩,研究组在基础治疗上使用我科中药协定方超声雾化熏蒸后立即进行睑板腺按摩,每周治疗1次,疗程2个月,比较治疗前后干眼症症状、角膜荧光素染色(Fluorescent Test,FL)、视功能损害眼病患者生活质量量表(The Quality of Life Scale for Disease with Visual Impairment,SQOL-DVI)评分、泪膜破裂时间(Break-up Time,BUT)和泪液分泌试验(Schirmer I Test,SIt)情况。结果:治疗后,研究组干眼症状有效率高于对照组,差异有统计学意义(P <0.05);治疗后,两组FL、BUT、SIt的差异无统计学意义(P> 0.05),但研究组SQOL-DVI评分高于对照组,差异有统计学意义(P <0.05)。结论:中药超声雾化熏蒸联合睑板腺按摩能明显改善MGD患者的干眼症状,提高患者的生活质量。

Objective: To evaluate the efficacy of TCM medicine ultrasonic atomization fumigation combined with palpebrae gland massage on MGD. Methods: A total of 280 MGD patients from September 2019 to September 2020 were randomly divided into the study group and the control group. Both groups received basic treatment, the study group was treated by TCM prescription ultrasonic atomization fumigant for basic treatment and immediately performed meibomian gland massage. The treatment is performed once a week for two months. The symptoms of xerophthalmia, FL, SQOL-DVI score, BUT and SIt were compared before and after treatment. Results: After treatment, the effective rate of dry eye symptoms in the study group was higher than the control group, and the difference was statistically significant(P<0.05). After treatment, there was no statistical difference between the two groups in FL, BUt, and SIt(P>0.05), but the SQOL-DVI score in the study group was higher than the control group, and the difference is statistically significant(P<0.05). Conclusion:TCM medicine ultrasonic atomization fumigation combined with meibomian gland massage can significantly relieve the symptoms of dry eyes in MGD patients, and improve the quality of life of patients.