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金水相生法干预治疗支气管哮喘缓解期的Meta分析 被引量:1

A meta-analysis of treating bronchial asthma in remission stage by the Jinshui Xiangsheng method
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摘要 目的:研究通过Meta分析的方法,对近年来运用金水相生法干预治疗支气管哮喘缓解期的有效性以及安全性进行客观评价,以期为今后应用金水相生法治疗本病提供更多的循证依据。方法:利用计算机检索中国知网、万方数据库、维普数据库,收集以单纯的西医治疗为对照组,以金水相生法干预联合西医治疗为试验组的治疗支气管哮喘缓解期的随机对照试验。采用改良版的Jadad量表对纳入的研究进行质量评价,并使用RevMan 5.3软件对临床总有效率、中医证候总积分、肺功能指标、哮喘控制测试(Asthma Control Test,ACT)评分以及不良反应进行分析。结果:经过筛选共纳入29篇随机对照试验研究,纳入病例共2 570例。Meta分析结果显示:与单纯的西医治疗相比,金水相生法干预联合西医治疗能够显著提高临床总有效率,降低支气管哮喘患者的中医证候总积分,提高患者的肺功能指标,提高患者的ACT评分(均P <0.000 01),且安全性良好。结论:金水相生法干预治疗支气管哮喘缓解期优于单纯的西医治疗。 Objective:Through the meta-analysis,the effectiveness and safety of the Jinshui Xiangsheng method(金水相生法)in the treatment of bronchial asthma in remission stage in recent years was evaluated objectively in this study,in order to provide more evidence-based basis for the application of the method in treating the disease in the future.Methods:The computer was used to search the literature in CNKI,Wanfang and VIP databases to collect the randomized controlled trials of treating bronchial asthma in remission stage.The control group were given simple Western medicine,and the test group took the Jinshui Xiangsheng method plus Western medicine.The revised Jadad scale was used to analyze the quality of the included studies,and RevMan 5.3 software was used to analyze the total clinical efficiency,total score of TCM syndromes,pulmonary function indexes,ACT score and adverse reactions in each study.Results:After screening,a total of 29 randomized controlled trials with 2570 cases were included.The results of the meta-analysis showed that compared with mere Western medicine treatment,the Jinshui Xiangsheng method plus Western medicine could significantly improve the total efficiency,decrease the total score of TCM syndromes of patients with bronchial asthma,improve the pulmonary function indicators,and improve ACT score of the patients,with good safety.Conclusion:The intervention of the Jinshui Xiangsheng method on bronchial asthma in remission stage is better than mere Western medicine.
作者 付尧 李丁蕾 王祺 FU Yao
出处 《中医临床研究》 2022年第26期140-144,共5页 Clinical Journal Of Chinese Medicine
基金 辽宁省教育厅面上项目(LJKZ0889)。
关键词 支气管哮喘 缓解期 金水相生法 META分析 Bronchial asthma Remission stage The Jinshui Xiangsheng method Meta-analysis
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