肠道菌群失调与失眠症关联机制的研究进展

Review on the association mechanism of intestinal flora imbalance and insomnia

失眠症既可独立存在,又可继发于其他神经系统疾病或躯体疾病,其病因众多,且发病机制目前尚不十分明确。随着近年来认识的逐渐深入,越来越多的研究显示肠道菌群在失眠症的发生发展及药物治疗中起着重要作用。文章基于肠道菌群引起失眠症的可能作用机制,从失眠症患者与健康人肠道菌群的差异、肠道菌群在失眠症药物治疗中的作用及相关作用机制等角度分析肠道菌群对失眠症的影响。

Insomnia can exist independently, and can also be secondary to other neurological diseases or physical diseases. There are many causes of insomnia, and the pathogenesis is still not very clear. With the gradual deepening of understanding in recent years, more and more studies have shown that intestinal flora plays an important role in the occurrence, evolution and medicine treatment of insomnia. In this article, based on the possible action mechanism of intestinal flora on insomnia, the role of intestinal flora in the treatment of insomnia was analyzed from the perspectives of the difference of intestinal flora between insomnia patients and healthy people, and the influence of intestinal flora on insomnia and the related action mechanism.