肾透明细胞癌MSCT影像学征象评估病理分级的可行性研究

Feasibility that MSCT Imaging Signs of Renal Clear Cell Carcinoma Are Used to Evaluate Pathological Hrade

目的研究肾透明细胞癌多层螺旋CT(MSCT)影像学征象评估病理分级的可行性。方法选取本院2017年9月至2019年7月收治38例肾透明细胞癌患者作为研究对象,根据世界卫生组织(WHO)/国际泌尿病理学会(ISUP)病理学分级将患者分为低级别组和高级别组,对比分析肾透明细胞癌病理高低级别MSCT征象。结果低级别组患者与高级别组患者肿瘤最大径、平扫CT值、强化均匀、有假包膜等MSCT征象比较无差异(P>0.05);低级别组患者肿瘤形态、密度、皮髓交界期强化程度、皮髓交界期肿瘤实质与同侧正常肾皮质CT值差及实质期肿瘤实质与皮髓交界期瘤实质CT值差比较有差异(P<0.05)。结论MSCT可清楚显示肾透明细胞癌的影像学特征,其影像学征象与病理学分级具有一定的相关性,可为临床上初步诊断肾透明细胞癌提供可靠的依据。

Objective To study the feasibility that imaging signs of renal clear cell carcinoma in multislice spiral CT(MSCT)are used to evaluate pathological grade.Method 38 patients with renal clear cell carcinoma treated in our hospital from September 2017 to July 2019 were selected as research subjects.According to the pathological classification of World Health Organization(WHO)/International Society of Urological Pathology(ISUP),patients were divided into low-grade group and high-grade group,and the pathological grade and MSCT signs of renal clear cell carcinoma were compared and analyzed.Results There was no significant difference in the MSCT signs such as tumor diameter,CT scan value,homogeneity,enhancement,and pseudo-encapsulation between the low-grade group and high-grade group(P>0.05).There were differences in tumor shape,density,degree of enhancement in corticomedullaryphase,CT value difference between parenchyma of tumour and psilateral normal renal cortex in corticomedullaryphase and the CT value difference of tumour parenchyma between nephrographic phase and corticomedullaryphase in low-grade group(P<0.05).Conclusion MSCT can clearly show the imaging characteristics of renal clear cell carcinoma,and its imaging signs have some correlation with pathological grade,which can provide a reliable basis for the preliminary clinical diagnosis of renal clear cell carcinoma.