胎儿体重与初产妇压力性尿失禁的相关性研究

Study on the correlation between fetal weight and postpartum stress urinary incontinence of primipara

目的分析胎儿体重以及巨大儿与初产妇发生压力性尿失禁(stress urinary incontinence,SUI)的相关性。方法选取2018年6月至2021年1月在中山大学附属第七医院和宝安区石岩人民医院行盆底超声检查的449例患者为研究对象,收集患者基本资料、基础疾病史、分娩相关信息、产后相关信息以及盆底超声检查结果。运用R软件以及Empower(R)软件,分析SUI的影响因素,运用多因素回归分析模型调整混杂因素后分析胎儿体重以及巨大儿与初产妇发生SUI的相关性。结果共有65例(14.48%)出现SUI。调整混杂因素后,多因素回归分析结果显示胎儿体重与SUI的发生有相关性(OR=2.24,95%CI:1.07-4.68,P=0.032)。与分娩胎儿体重<4kg的产妇相比,分娩巨大儿(体重≥4kg)的产妇产后发生SUI的风险会增加3.11倍(OR=4.11,95%CI:1.03-16.45,P=0.046)。结论胎儿体重与初产妇产后发生SUI存在相关性,尤其是胎儿体重超过4kg时,产妇发生SUI的风险将增加3.11倍。

Objective To analyze the association between fetal weight, macrosomia and stress urinary incontinence(SUI)in primipara.Methods 449 patients who underwent pelvic floor ultrasound examination in the Seventh Affiliated Hospital of Sun Yat-Sen University and Shiyan People’s Hospital of Bao’an District from June 2018 to January 2021 were selected as the research objects, all patients’ clinical records were reviewed, including: basic information, history of underlying diseases, childbirth-related information, postpartum-related information, and pelvic floor ultrasonography results.Using R software and Empower(R) software, the influencing factors of SUI were analyzed, and the multivariate regression analysis model was used to adjust the confounding factors to analyze the correlation between fetal weight and macrosomia and SUI in primiparas.Results There were 65(14.48%) patients with SUI.After adjusting for the confounding factors, multiple regression analysis showed that there was correlation between fetal weight and SUI(OR=2.24,95% CI:1.07-4.68,P=0.032).Compared with primipara with fetal weight<4 kg, the primipara with macrosomia would increase the risk of SUI by 3.11 folds(OR=4.11,95% CI:1.03-16.45,P=0.046).Conclusions There is correlation between fetal weight and SUI in primipara.Especially, when the fetal weight over 4 kg, the risk of SUI for the primipara will increase 3.11 folds.