高血压心脏病和肥厚型心肌病的FT-CMR定量分析

FT- CMR analysis of hypertensive heart disease and hypertrophic cardiomyopathy

目的:研究心血管磁共振心肌特征追踪(FT-CMR)定量分析高血压心脏病(HHD)和肥厚型心肌病(HCM)的价值。方法:随机选取2019年1月至2020年1月于我院心内科就诊的50例左室心肌肥厚的HHD患者(HHD组)和50例左室心肌肥厚的HCM患者(HCM组)为研究对象。比较两组患者的临床资料、实验室检查指标及FT-CM定量分析结果等。结果:HHD组口服血管紧张素转化酶抑制剂/血管紧张素受体拮抗剂(ACEI/ARB)的患者比例、收缩压、右心室(RV)收缩末期直径高于HCM组,HHD组患者胆固醇(TC)、左心室(LV)质量指数、LV前壁厚度、LV最大壁厚及钆对比剂延迟增强比例低于HCM组,差异具有统计学意义(均P<0.05)。结论:在FT-CMR定量分析中两组主要差异表现为HHD组的RV收缩末期直径显著大于HCM组,LV质量指数、LV前壁厚度、LV最大壁厚及钆对比剂延迟增强比例低于HCM组。

Objective: To study the value of feature-tracking cardiac magnetic resonance(FT-CMR) quantitative analysis on hypertensive heart disease(HHD) and hypertrophic cardiomyopathy(HCM). Methods: From January 2019 to January 2020, 50 HHD patients with left ventricular(LV) hypertrophy(HHD group) and 50 HCM patients with LV hypertrophy(HCM group) who visited the department of cardiology in our hospital were randomly selected as the research objects. The clinical data, laboratory test indexes and quantitative analysis results of FT-CMR were compared between the two groups. Results: The proportion of patients receiving oral angiotensin converting enzyme inhibitor/angiotonin receptor blocker(ACEI/ARB), systolic blood pressure, right ventricular(RV) contraction and the end-stage diameter in HHD group were higher than those in the HCM group, and the total cholesterol(TC), LV mass index, LV anterior wall thickness, LV maximum wall thickness and gadolinium contrast agent delayed enhancement ratio in the HHD group were lower than those in the HCM group. The differences were all statistically significant(P<0.05). Conclusion: In the quantitative analysis of FT-CMR, the main difference between the two groups is the RV end-systolic diameter of HHD group significantly higher than that of HCM group, The LV mass index, LV anterior wall thickness, LV maximum wall thickness and the ratio of delayed enhancement of gadolinium contrast agent were lower than those of HCM.