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晚期肝癌的免疫检查点抑制剂研究现状

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摘要 肝癌是全球常见的恶性肿瘤之一,发病率和死亡率均较高,早期起病隐匿,发现时已处于中晚期,失去手术机会,预后差。近年来,随着对肿瘤免疫逃逸机制的深入研究,发现免疫检查点在肿瘤逃逸中发挥了重要作用,许多针对晚期肝癌患者的免疫检查点抑制剂(Immune Checkpoint Inhibitors,ICI)正在临床研发中,且有些药物已经被证明可以改善晚期肝癌患者的预后。本文就ICI治疗晚期肝癌的现状作一系统综述。
出处 《江西医药》 CAS 2022年第8期998-1001,共4页 Jiangxi Medical Journal
基金 江西省教育厅科学技术研究项目,编号GJJ170018。
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