氟苯虫酰胺在大白菜中的残留、消解动态及长期膳食风险评估

Residue Dissipation and Dietary Risk Assessment of Flubendiamide in Chinese Cabbage

为评价氟苯虫酰胺在大白菜上使用的安全性,开展了氟苯虫酰胺在大白菜中的残留量及消解动态研究,进行了1年6地田间试验,消解动态试验按氟苯虫酰胺76.5g a.i./ha(1.5倍推荐最高施药量),最终残留试验按氟苯虫酰胺51g a.i./ha(推荐最高施药量)和76.5g a.i./ha(1.5倍推荐最高施药量)施药,施药3~4次,施药间隔10d,施药后3、5、7d采集大白菜样品。利用高效液相色谱—质谱联用法定量分析检测。检测结果表明:氟苯虫酰胺在大白菜中的半衰期为6.4~9.8d,氟苯虫酰胺在距离最后施药7d采样时大白菜中残留量为<0.01~5.14mg/kg。长期膳食风险评估结果表明:氟苯虫酰胺在登记作物中的总膳食评估值为0.13,长期膳食风险在可接受范围内,说明氟苯虫酰胺在大白菜中的残留不会对我国人体健康产生影响。

In order to evaluate the safety of the use of flubendiamide in Chinese cabbage,The supervised residue trials were conducted to study the residue and degradation dynamic of flubendiamide in Chinese cabbage.The trials were conducted at the six sites during one year.For the degradation dynamics trials,flubendiamide was sprayed at the concentration of 76.5 g a.i./ha(1.5 times recommended concentration).For the final residue trials,flubendiamide was applied 3~4 times with the spraying interval of 10 d at the application rate of 51 g a.i./ha and 76.5 g a.i./ha respectively,corresponding to the recommended concentration and 1.5 times recommended concentration.Chinese cabbage was sampled after 3,5 and 7 d of application.Flubendiamide was analyzed by LC-MS/MS.The results of the degradation dynamics study showed that the half-life values(t)were 6.4 d and 9.8 d in Shandong and Hebei,respectively.After 7 days of last application,the ultimate residue of flubendiamide in Chinese cabbage was at the range of<0.01~5.14 mg/kg.The dietary intake risk assessment showed that the dietary exposure risk index of flubendiamide in Chinese cabbage was 0.13,which indicated that the dietary exposure risk was at an acceptable level.