摘要
Investigations into the intramolecular interactions of the native protein in solution are important to understand its structural stability as well as its potential uses in future applications.In this study,we used a bacterial two-hybrid system to investigate the interaction between the phycocyanin𝛼and𝛽subunits that form the phycocyanin monomer.Key amino acid residues responsible for the interaction between the subunits were identified,providing direct experimental evidence for the intramolecular interaction.
基金
supported by the National Science Foundation of China(31900023,U2006205)
the State Key Laboratory of Microbial Technology Open Projects Fund(M2021-08).
