代谢对肿瘤转移影响的研究进展

Research progress on the effect of metabolism on tumor metastasis

近年来,肿瘤治疗领域取得了一定进展,但肿瘤转移仍是患者死亡的主要原因。肿瘤细胞在转移级联过程中会动态地调节新陈代谢,以适应不同转移阶段的能量需求。因此,靶向转移过程中的代谢特征可能为预防和治疗肿瘤转移提供了机会。本文将首先介绍肿瘤转移过程中与代谢相关的最新进展,然后重点综述与肿瘤代谢密切相关的几种营养物质在肿瘤侵袭、转移过程中的意义,以帮助相关人员了解最新的研究进展,并展望靶向代谢途径的治疗策略的可能性。

In recent years,people have made some progress in the field of tumor treatment,but tumor metastasis is still the main cause of death.In the process of metastasis cascade,tumor cells will dynamically regulate metabolism to meet the energy needs of different metastasis stages.Therefore,targeting the metabolic characteristics in the process of tumor metastasis may provide an opportunity to prevent and treat tumor.This paper will firstly introduce the latest progress related to metabolism in the process of tumor metastasis,and then focus on the significance of several nutrients closely related to tumor metabolism in the process of tumor invasion and metastasis,to help relevant personnel understand the latest research progress and look forward to the possibility of treatment strategies targeting metabolic pathways.