摘要
Intestinal diseases that have high mortality and morbidity rates and bring huge encumbrance to the public medical system and economy worldwide,have always been the focus of clinicians and scientific researchers.Early diagnosis and intervention are valuable in the progression of many intestinal diseases.Fortunately,the emergence of sensor materials can effectively assist clinical early diagnosis and health monitoring.By accurately locating the lesion and sensitively analyzing the level of disease markers,these sensor materials can help to precisely diagnose the stage and state of lesions,thereby avoiding delayed treatment.In this review,we provide comprehensive and in-depth knowledge of diagnosing and monitoring intestinal diseases with the assistance of sensor materials,particularly emphasizing their design and application in bioimaging and biodetection.This review is dedicated to conveying practical applications of sensor materials in the intestine,critical analysis of their mechanisms and applications and discussion of their future roles in medicine.We believe that this review will promote multidisciplinary communication between material science,medicine and relevant engineering fields,thus improving the clinical translation of sensor materials.
基金
This work was supported by the National Key Research and Development Program of China(Grant Nos.2020YFA0908200 and 2020YFB1313100)
the National Natural Science Foundation of China(Grant No.22002018)
the Innovative Research Team of High-level Local University in Shanghai,Guangdong Basic Application Research Fund Project(2019A1515110925)
the Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning(Grant No.SSH1340011).
