摘要
目的探讨幕上胶质瘤患者预后与侧脑室累及与否的关系。方法回顾性分析蚌埠医学院第一附属医院神经外科自2018年1月至2021年8月手术治疗的60例幕上胶质瘤患者的临床资料。根据MRI显示侧脑室是否受侵犯分为累及组(26例)与未累及组(34例),比较两组患者术后全切率、手术时间、住院时间、术后病理类型、术后复发和术后生存率的差异。结果累及组与未累及组肿瘤全切比例分别为73.05%、82.35%,差异无统计学意义(P>0.05)。两组患者手术时间和术后住院时间,差异有统计学意义(P<0.05)。两组患者术后病理级别类似,差异无统计学意义(P>0.05)。术后随访4~33个月,累及组随访21例,复发6例,未累及组随访26例,复发2例。Kaplan-Meier生存分析提示两组生存率差异有统计学意义(P<0.05)。结论累及侧脑室的胶质瘤手术时间及住院时间较长,预后较差。
Objective To investigate the relationship between lateral ventricle involvement and prognosis in patients with supratsural glioma.Methods The clinical data of 60 glioma patients treated with surgery from January 2018 to August 2021 in the First Affiliated Hospital of Bengbu Medical College were analyzed retrospectively.Among them,twenty-five patients with lateral ventricle involvement were assigned as involvement group and 34without lateral ventricle involvement as non-involvement group according to the MRI results.They were compared in terms of total resection rate,surgical duration,hospitalization,postoperative pathological type,postoperative recurrence and postoperative survival rate.Results The rate of total resection had no significant difference between the two groups(73.05%vs.82.35%,P>0.05).The duration of surgery and postoperative hospital stay were significantly different(P<0.05).The postoperative pathological grade was insignificantly different between the two groups(P>0.05).Postoperative follow-up was 4~33 months.Twenty-one patients in the involvement group were followed up,with 6 cases of relapse,and 26 in the non-involvement were followed up,with 2 cases of relapse.Kaplan-Meier survival analysis showed significant difference in the survival rate between the two groups(P<0.05).Conclusion For those patients with supratentorialglioma involving lateral ventricle,the time for both operations and hospital stay is longer and the prognosis is poorer.
作者
张业森
杜帮
娄飞云
苏贺先
张少军
姜之全
韩易
ZHANG Yesen;DU Bang;LOU Feiyun;SU Hexian;ZHANG Shaojun;JIANG Zhiquan;HAN Yi(Depart-ment of Neurosurgery,the First Affiliated Hospital,Bengbu Medical College,Bengbu 233004,China)
出处
《实用医学杂志》
CAS
北大核心
2022年第16期2009-2012,共4页
The Journal of Practical Medicine
基金
安徽省高等学校自然科学研究一般项目(编号:KJ2015B060by)。
关键词
胶质瘤
侧脑室
预后
glioma
lateral ventricle
prognosis