摘要
人体内的褪黑素主要是一种内源性吲哚胺类激素,具有多种生理功能。褪黑素除在治疗睡眠障碍方面发挥重要作用之外,还在治疗神经系统疾病、癌症、心血管系统疾病以及骨骼疾病等方面发挥重要作用。本文将基于褪黑素的人体网络机制和临床应用现状进行总结,探讨其进一步临床应用研究的重要问题聚焦点与方向。
Melatonin is mainly an endogenous indoleamine hormone with many physiological functions.Melatonin not only plays an important role in the treatment of sleep disorders,but also plays an important role in the treatment of nervous system diseases,cancer,cardiovascular diseases,and bone diseases.In this paper,the human body networks mechanisms and the clinical applications of melatonin were summarized to provide reference for exploring the focus and direction of further clinical application research.
作者
邵明坤
刘蓉
孙品
关水
廖炳灿
李莎
丛滔
梁凯
马辉
孙长凯
SHAO Mingkun;LIU Rong;SUN Pin;GUAN Shui;LIAO Bingcan;LI Sha;CONG Tao;LIANG Kai;MA Hui;SUN Changkai(RECCE-TPM-HPM,School of Biomedical Engineering,Dalian University of Technology,Dalian 116024,Liaoning,China;Department of Pharmacy,the Second Hospital of Dalian Medical University,Dalian 116027,Liaoning,China;Department of Neurosurgery,Huashan Hospital of Fudan University,Shanghai 200040,China;Department of Hematology,the First Hospital of Dalian Medical University,Dalian 116011,Liaoning,China)
出处
《中国临床药理学与治疗学》
CAS
CSCD
2022年第9期1031-1040,共10页
Chinese Journal of Clinical Pharmacology and Therapeutics
基金
国家科技部《科技创新2030-“新一代人工智能”重大项目:新一代神经网络模型》(No.2018AAA0100300)
国家自然科学基金(No.81801228)
上海市《脑与类脑智能基础转化应用研究》重大科技专项资助(No.2018SHZDZX01)。
关键词
褪黑素
人体网络机制
临床应用
melatonin
human body networks mechanisms
clinical applications
