肝多房棘球蚴病脉管侵犯的研究进展

Research progress on vascular invasion of hepatic alveolar echinococcosis

肝多房棘球蚴病病灶对人体重要的脉管系统(血管、胆管、淋巴结)是否侵犯及其侵犯程度,直接影响患者的手术治疗方式。目前,临床对于血管侵犯、胆管侵犯及淋巴结转移的病理状态、检查指征及治疗方式的关系尚不明确。本文综合国内外最新研究进展,对肝多房棘球蚴病的增殖与转移机制,病灶的病理分区,及脉管侵犯的肉眼、影像、显微镜下的特点进行深入阐述,以期推进肝多房棘球蚴病脉管侵犯诊断与治疗等研究的发展。

The surgical treatment for multilocular hepatic echinococcosis is determined by the severity of the lesion invasion to the important vascular system(blood vessels, bile ducts and lymph nodes). Currently, the clinical relationships among the pathological changes, examination indications and treatments of vascular invasion, bile duct invasion and lymph node metastasis are not clear. Here we have summarized recent advances worldwide in multilocular hepatic echinococcosis. The mechanisms of multilocular hepatic echinococcosis progression and metastasis,the pathological distribution of the lesions and the clinical imaging, the morphology and microscopic characteristics of the vascular invasion were reviewed. This review will shed light on the development and research of the diagnosis and treatment of vascular invasion caused by multilocular hepatic echinococcosis.