从循证医学与转化医学谈中医药临床研究发展

Discussion on the development of traditional Chinese medicine clinical research from evidence-based medicine and translational medicine

中医药是中华文明的瑰宝,优势在于临床以整体观念和辨证论治为指导思想,强调以人为本的理念,具有科学和人文的双重属性。临床疗效体现了中医药的生命力,近年来,研究者聚焦中医临床优势病种和优势疗法,掌握循证医学方法,建立符合中医药特点的临床疗效评价新方法、新技术,与国际临床研究模式接轨,获得共识认可。运用转化医学思路和方法,从需求和疗效出发,构建临床与基础的转化平台,提高临床服务水平,促进新药物、新技术开发。总之,中医药临床研究发展应坚持国学原理,弘扬原创思维,兼容并蓄,文明互鉴,和合互动,多学科交叉协作,迎接大科学、大卫生背景下高概念、大数据、信息智能两化融合新纪元,把握中医药从中西医汇通到中西医并重来之不易的发展形势,实现我主人随,传承创新。

Traditional Chinese medicine(TCM)is the treasure of Chinese civilization.Its advantage lies in clinical practice.It takes the concept of holism and treatment based on syndrome differentiation as the guiding ideology,emphasizes the people-oriented concept,and has the dual attributes of science and humanity.The clinical efficacy reflects the vitality of TCM.In recent years,the researchers focus on the TCM clinical regnant diseases and therapies,master the evidence-based medicine method,establish new methods and technologies for clinical efficacy evaluation in line with the characteristics of TCM,integrate with the international clinical research mode so as to gain consensus and recognition.Using the ideas and methods of translational medicine,starting from the needs and efficacy,to build a clinical and basic transformation platform,improve the quality of clinical services,and promote the development of new drugs and new technologies.In general,the development of TCM clinical research should adhere to the principles of Chinese Learning,carry forward original thinking,be fully inclusive and equitable,learn mutually,collaborate with each other,and cooperate in multi-disciplinarity,so as to welcome a new era of high concepts,big data,integration of information and intelligence under the background of big science and health,grasp the hard-won development trend of TCM from integration of TCM and western medicine to placing equal emphasis on TCM and western medicine,and realize the inheritance and innovation of TCM led by us.