主支支架联合边支预埋球囊介入治疗冠状动脉分叉病变患者的临床效果及预后研究

Clinical Effect and Prognosis of Main Branch Stent Combined with Side Branch Balloon Embedding for Intervention in Patients with Coronary Bifurcation Lesions

目的 分析主支支架联合边支预埋球囊介入治疗冠状动脉分叉病变患者的临床效果及预后。方法 收集2018年1月—2021年1月收治的105例急性心肌梗死分叉病变临床资料,根据治疗方式的不同分为研究组54例(予主支支架联合边支预埋球囊介入治疗)及对照组51例(予单导丝边支保护介入治疗)。比较2组手术成功率,心功能指标[左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、左室射血分数(LVEF)]及心源性死亡、再发心肌梗死、靶血管重建等不良心血管事件发生情况。结果 研究组手术成功率为94.44%高于对照组的80.39%(P<0.05)。治疗后研究组LVEDD、LVESD低于对照组,而LVEF高于对照组(P<0.01)。研究组不良心血管事件总发生率低于对照组(P<0.05)。结论 主支支架联合边支预埋球囊介入治疗冠状动脉分叉病变,能提高患者手术成功率,改善心功能,且预后良好。

Objective To analyze the clinical effect and prognosis of main branch stent combined with side branch balloon embedding in the treatment of coronary bifurcation lesions(CBLs).Methods The clinical data of 105 patients with acute myocardial infarction(AMI)with CBLs admitted from January 2018 to January 2021 were collected.They were divided into the research group(main branch stent combined with side branch balloon pre-embedding for interventional treatment,n=54)and the control group(single guidewire side branch protection strategy for interventional treatment,n=51)according to different treatment methods.The surgical success rate,cardiac function indicators[left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular ejection fraction(LVEF)],and adverse cardiovascular events such as cardiac death,recurrent myocardial infarction,target vascular remodeling were compared between the two groups.Results The surgical success rate of the research group was 94.44%,which was higher than that of the control group(80.39%),with a statistically significant difference(P<0.05).After treatment,LVEDD and LVESD in the research group were lower than those in the control group,while LVEF was higher than that in the control group(P<0.01).The total incidence of adverse cardiovascular events in the research group was lower than that in the control group(P<0.05).Conclusion The main branch stent combined with the side branch balloon pre-embedding for the treatment of CBLs can improve the success rate of the operation,improve the cardiac function,and has a good prognosis.