社区老年人认知衰弱危险因素的meta分析

Meta analysis of risk factors for cognitive frailty among community-dwelling elderly people

目的通过meta分析明确社区老年人发生认知衰弱(CF)的影响因素。方法检索中国知网、万方数据、维普、中国生物医学文献服务系统(SinoMed)、Web of Science、Cochrane Library、PubMed、Embase和CINHAL数据库中研究60岁及以上社区老年人CF影响因素的文献。由两名研究员分别根据纳入排除标准筛选文献,评价文献质量,提取资料,对符合标准的文献使用RevMan5.3软件进行分析。结果共纳入文献13篇,总样本量22323例,CF组1222例,非CF组21101例,纳入13个因素分析。Meta分析结果显示,高龄、年龄>75岁、年龄>80岁、患病情况、睡眠问题、抑郁、营养状态差、跌倒史、低起立行走试验(TUG)评分是社区老年人CF的危险因素(P<0.05);规律运动、男性是CF的保护因素(P<0.05);文化程度、低日常生活能力(ADL)评分与社区老年人CF的发生无明显相关性(P>0.05)。结论在社区工作中应重视CF发生的影响因素,充分预测和识别高危CF人群,预防CF的发生,从而预防社区老年人的不良后果。

Objective To identify the influencing factors of cognitive frailty(CF)in the community-dwelling elderly people by conducting a meta analysis.Methods The literatures on the influencing factors of CF among the community-dwelling elderly people aged 60 years and over were retrieved from the databases,including the China National Knowledge Infrastructure(CNKI),WanFang Data,VIP Database,Chinese Biomedical Literature Service System(SinoMed),Web of Science,Cochrane Library,PubMed,Embase and CINHAL database.Two researchers screened the literatures according to the inclusion and exclusion criteria,evaluated the quality of the literatures,extracted the data,and analyzed the literatures meeting the criteria by using RevMan5.3 software.Results A total of 13 articles were included,with a total sample size of 22323 cases,including 1222 cases in the CF group and 21101 cases in the non-CF group.Thirteen factors were included in the analysis.The meta analysis results showed that the advanced age,age>75 years old,age>80 years old,disease status,sleep problems,depression,poor nutritional status,history of falls,and low timed up and go(TUG)test score were the risk factors for CF among the community-dwelling elderly people(P<0.05),the regular exercise and male gender were the protective factors for CF(P<0.05),and the educational level and low ability of daily living(ADL)score had no significant correlation with the CF occurrence among the community-dwelling people(P>0.05).Conclusion In the community work,attention should be paid to the influencing factors of CF occurrence,fully predict and identify the high-risk CF population,and prevent the occurrence of CF,so as to preventing the adverse consequences of the community-dwelling elderly people.