摘要
糖尿病是影响人类生命健康的重要代谢障碍性疾病,其发生发展与微循环障碍密切相关,微循环障碍也是发生糖尿病视网膜病变、糖尿病肾病、糖尿病周围神经病变等多种慢性并发症的病理基础,“血中伏火”理论由“脾胃学说”的创始人李东垣提出,本文基于此探讨糖尿病及其微循环障碍的病机演变过程。脾胃虚弱“阴火”鸱张为发病之本,“血中伏火”是糖尿病及其微循环障碍形成的关键,血中伏火、煎熬津液可酿生瘀血、痰湿等病理产物,导致微血管结构异常、血流速度改变、血液黏稠不畅,从而并发微循环障碍及糖尿病并发症,微循环障碍反过来也使痰湿瘀胶痼互结形成恶性循环而加重病情。
Diabetes is an important metabolic disorder that affects human life and health.The development of diabetes is closely related to microcirculation disorders.Microcirculation disturbance is also the pathological basis of various chronic complications such as diabetic retinopathy,diabetic nephropathy,and diabetic peripheral neuropathy.The theory of"Fire in blood"was put forward by Li Dongyuan,the founder of"Spleen and Stomach Theory".Based on this,this article discusses the pathogenesis of diabetes and its microcirculation disorders.Weak spleen and stomach,"Yin fire"is flaming,which is the root of disease"Fire in the blood"is the key to the formation of diabetes and its microcirculation disorders.Fire in the blood and torment of body fluid can cause pathological products such as blood stasis,phlegm and dampness,resulting in abnormal microvascular structure,changes in blood flow speed,and poor blood viscosity,which can lead to microcirculation disorders and complications of diabetes.In turn,the microcirculation disorder also causes the phlegm,dampness and blood stasis to condense together,forming a vicious circle and aggravating the condition.
作者
李嘉鑫
杨宇峰
王金曦
付子珊
周方圆
石岩
LI Jiaxin;YANG Yufeng;WANG Jinxi;FU Zishan;ZHOU Fangyuan;SHI Yan(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China)
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2022年第9期1413-1415,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
国家重点基础研究发展计划项目(2013CB532004)-中医应用理论框架结构研究
辽宁省“百千万人才工程”资助项目(2020921039)-核受体FXR调控2型糖尿病胰岛素抵抗的分子机制及益糖康干预作用研究。
关键词
血中伏火
脾胃虚弱
糖尿病
微循环障碍
Latent fire in blood
Weak spleen and stomach
Diabetes
Microcirculation disorders