海德堡三角清扫胰十二指肠切除术在胰头癌治疗中的应用效果分析

Application Effect Analysis of Heidelberg Triangle Dissection Pancreaticoduodenectomy for Pancreatic Head Cancer

目的:探讨海德堡三角清扫胰十二指肠切除术在胰头癌中的应用效果。方法:回顾性分析2016年1月-2019年2月徐州医科大学附属医院收治的60例胰头癌患者的资料,按治疗方式将其分对照组和观察组,各30例。对照组接受标准根治性胰十二指肠切除术治疗,观察组接受海德堡三角清扫胰十二指肠切除术治疗。比较两组围手术期指标、生存情况、病灶复发情况及并发症发生情况等。结果:术前,两组肝功能指标比较,差异均无统计学意义(P>0.05);术后1 d,两组肝功能指标较治疗前均降低,且观察组均低于对照组(P<0.05)。观察组手术时间长于对照组,术中出血量少于对照组(P<0.05);两组住院时间比较,差异无统计学意义(P>0.05)。观察组术后1、3年生存率均高于对照组,复发率均低于对照组(P<0.05)。观察组并发症发生率为16.67%,虽低于对照组的20.00%,但差异无统计学意义(P>0.05)。结论:海德堡三角清扫胰十二指肠切除术治疗胰头癌,在不增加并发症发生率的基础上,能进一步降低复发率,延长患者生存时间。

Objective:To investigate the application effect of Heidelberg triangle dissection pancreaticoduodenectomy for pancreatic head cancer.Method:The data of 60 patients with pancreatic head cancer admitted to the Affiliated Hospital of Xuzhou Medical University from January 2016 to February 2019 were retrospectively analyzed,and they were divided into the control group and the observation group according to treatment modality,30 cases in each group.And the control group was given standard radical pancreatoduodenectomy,the observation group was given Heidelberg triangle dissection pancreaticoduodenectomy.The perioperative indexes,survival status,status of lesion recurrence,and complications were compared between two groups.Result:Before operation,there were no significant differences in liver function between two groups (P>0.05);at 1 d after operation,the liver function indicators of two groups were lower than those before treatment,and the observation group were lower than those of the control group (P<0.05).The operation time of the observation group was longer than that of the control group,and the intraoperative bleeding volume was less than that of the control group (P<0.05);there was no significant difference in hospitalization time between two groups (P>0.05).The 1-year and 3-year survival rates in the observation group were higher than those in the control group,and the recurrence rate was lower than that in the control group (P<0.05).The complication incidence rate in the observation group was 16.67%,which was lower than that of the control group by 20.00%,but the difference was not statistically significant (P>0.05).Conclusion:Heidelberg triangle dissection pancreaticoduodenectomy in the treatment of pancreatic head cancer,it can further reduce the recurrence rate and prolong the survival time based on not increasing the complication rate.