新型物质在抗感染领域的应用前景

Application prospect of new substances in anti-infection field

抗菌药物的不合理使用导致耐药菌感染再次成为影响人类健康的一大危机。虽然近些年研发了一些新型抗菌药物,但耐药菌也紧随其后出现,目前急需替代性物质来应对这一危机。研究发现新型纳米材料和生物聚合物有抗菌性能,这些物质具有体积小、可降解、生物利用度高以及毒副作用低等特点,可为抗菌药物的节约型用药和预防耐药菌的出现提供新方向。因此,本文综述了这些新型物质的抗菌特点、作用机制和目前的研究现状,旨在为这些物质的进一步研究和未来在抗感染领域的应用提供指导。

The irrational use of antibiotics leads to the infection of drug-resistant bacteria,which has once again become a major crisis affecting human health.Although some new antibiotics have been developed in recent years,bacterial resistance has also emerged soon afterwards.At present,alternative substances are urgently needed to deal with this crisis.Studies have found that innovative nanomaterials and biopolymers have antibacterial properties.These substances have the characteristics of small size,degradability,high bioavailability,and low side effects.They can provide new opportunities for economical use of antibiotics and prevention of drug-resistant bacteria.Therefore,this article reviewed the antibacterial characteristics,mechanism of action and current research status of these new substances,aiming to provide guidance for the further research of these substances and their future applications in the field of anti-infection.