摘要
一、本文实验证明,蛇岛产蝮蛇毒中提取的精氨酸酯酶对狗血液中粘度、红细胞压积、血浆纤维蛋白原,甘油三酯均有明显下降作用(P<0.05~0.01)。二、药物浓度以0.01g/kg体重计算为好。药物在血液中有效时间为9~12小时左右。为了保持血液中一定下降值,应以持续给药为好。该实验为今后临床开展治疗血栓、高凝血症等疾病,提供了参考数据。
The arginine csterase,purified from the snake venom of the Snake Island snakes,was studied in its anticoagulation effect.12 dogs were tested,The results showed that the viscosity and the contents of fibrinogen and lipid in blood were reduced in various degrees.It is proposed that this enzyme may be used for the treatment of various types of blood diseases,such as high blood viscosity,and thrombosis.
作者
郝文学
邹平公
韩天相
Hao Wen-xue;Zou Ping-gong;Han Tian-xiang(Chinese Medical College;The 406 Hospital of Navy)
