对正畸诱导性牙根吸收生物层面的认识

Biological Insights into Orthodontically Induced Root Resorption

正畸诱导性牙根吸收是正畸矫治力引发的以牙骨质等牙体组织破坏为主要特征的常见并发症,其主要由正畸矫治力诱导的局部无菌炎症而引起,进展过程受到了多种细胞及相关分子的复杂调控。由于正畸诱导性牙根吸收发病率高,潜在影响患者牙周组织健康,因此应受到正畸医生高度重视。本文着重于从生物层面对正畸诱导性牙根吸收进展特点、主要参与的细胞和相关调控分子及牙骨质的修复进行讨论。

Orthodontically induced root resorption is a common complication caused by orthodontic force,which is mainly characterized by the destruction of cementum and other dental tissues.It is mainly caused by local aseptic inflammation induced by orthodontic force and regulated by multiple cells and related molecules.Orthodontically induced root resorption is highly concerned by orthodontists due to its high incidence and potential impact on the health of periodontal tissues.In this article,biological characteristics of the progress of orthodontically induced root resorption,the main involved cells,related regulatory molecules,and cementum repair are described.