腹腔镜胃癌根治术与开腹胃癌根治术治疗早期胃癌的临床对比

Clinical comparison of laparoscopic and open surgery in the treatment of early gastric cancer

目的探究腹腔镜胃癌根治术与开腹胃癌根治术治疗早期胃癌的疗效。方法选择2018年7月至2021年6月宾阳县人民医院收治的60例早期胃癌患者,根据随机数字表法分为两组各30例,对照组采用开腹手术,观察组采用腹腔镜胃癌根治术,比较两组患者手术相关指标、术后恢复、免疫功能及术后并发症发生情况。结果观察组患者术中出血量少于对照组(P<0.05),手术时间长于对照组(P<0.05);两组患者淋巴结清扫数目无显著差异(P>0.05)。观察组患者的术后排气时间、排便时间、下床活动时间、住院时间均短于对照组(P<0.05),术后外周血IgA、IgM及IgG水平低于对照组(P<0.05)。观察组患者的术后并发症率为3.33%,低于对照组的20.00%(P<0.05)。结论腹腔镜胃癌根治术能取得与开腹胃癌根治术相似的近期疗效,且可减少术中出血量,缩短术后恢复时间,减轻免疫功能受损,减少术后并发症发生。

Objective To explore the efficacy of laparoscopic radical gastrectomy and open radical gastrectomy in the treatment of early gastric cancer.Method 60 patients with early gastric cancer treated in Binyang People's Hospital from July 2018 to June 2021 were randomly divided into two groups according to the random number table method,with 30 cases in each group.The control group was treated with open radical gastrectomy and the observation group was treated with laparoscopic radical gastrectomy.The operation related indexes,postoperative recovery,immune function and postoperative complication rate were compared between the two groups.Result The intraoperative blood output of the observation group was lower than that of the control group(P<0.05),the operation time of the observation group was longer than that of the control group(P<0.05),and there was no difference in the number of lymph node dissection between the two groups(P>0.05).The postoperative exhaust time,defecation time,out of bed activity time and hospital stay in the observation group were shorter than those in the control group(P<0.05).The peripheral blood IgA,IgM and IgG in the observation group were lower than those in the control group(P<0.05).The postoperative complication rate in the observation group was 3.33%,lower than 20.00%in the control group(P<0.05).Conclusion Laparoscopic radical gastrectomy can achieve the short-term effect similar to open radical gastrectomy,reduce the amount of intraoperative bleeding,shorten the postoperative recovery time,reduce the damage of immune function and reduce the incidence of postoperative complications.