摘要
Dear Editor,Colorectal cancer(CRC)is the second leading cause of cancer death according to the World Health Organization.Patients with inflammatory bowel disease(IBD),ulcerative colitis(UC)or Crohn’s disease(CD)are at increased risk of developing colitis-associated CRC(CAC)[1];however,our understanding of the inflammationcancer interplay at the molecular level is still limited.
基金
the MCIN/AEI/10.13039/501100011033(PID2019-108349RB-100 and SAF2016-79792R)to AC and JJSE
Villum Foundation,grant no.13152 to KA
by Agencia Estatal de Investigación(PID2019-104867RBI00/AEI/10.13039/501100011033)and the Instituto de Salud Carlos III-Fondo Europeo de Desarrollo Regional(CIBERONC/CB16/12/00273 and ICI20/00057)to AM and AB.PF received MCIN FPI fellowship(BES-2017-080139).