某院住院肾透析患者2016年至2020年合理用药分析

Rationality of Drug Use for Patients Underwent Renal Dialysis in a Hospital from 2016 to 2020

目的了解医院住院肾透析患者用药的合理性。方法通过医院信息系统提取某院2016年至2020年8873例住院肾透析患者的用药数据,按药品分类统计用药金额和总使用量,计算用药频度(DDDs),并按用药金额和DDDs分别降序排序,取排名前50的药品数据进行分析。结果5年间,该院住院肾透析患者数由1925例降至1428例,人均住院总费用由4.26万元降至4.02万元,人均药品费用由1.64万元降至1.22万元,占住院总费用比例由38.50%降至30.35%。5年间,用药金额排名前50的药品总金额总体呈降低趋势(由2180.46万元降至1139.90万元);肾病用药、抗菌药物、消化系统用药、心血管系统用药均为患者历年主要用药类别,且除2019年(仅次于抗菌药物)外,肾病用药的用药金额均最高;连续5年均排名前50的药品共15种,包括8个类别。5年间,DDDs排名前50药品的DDDs总值呈降低趋势(由32.65×10^(4)降至16.84×10^(4));DDDs连续排名前3的均为肾病用药、心血管系统用药、消化系统用药;连续5年均排名前50的药品共21种,包括7个类别。结论该院肾透析患者所用大多数药物均针对患者的主要病症及常见并发症,用药合理性较高。

Objective To understand the rationality of drug use for patients underwent renal dialysis in a hospital.Methods The drug use data of 8873 inpatients underwent renal dialysis in a hospital from 2016 to 2020 were extracted through the hospital information system(HIS).The drug consumption sum and total use amount were counted according to the drug classification,the defined daily doses(DDDs)were calculated,the drug consumption sum and DDDs were sorted in descending order to select the data of top 50 drugs for analysis.Results During the five years,the number of inpatients underwent renal dialysis in the hospital decreased from 1925 to 1428,the total hospitalization cost per capita decreased from CNY 42600 to CNY 40200,the drug cost per capita decreased from CNY 16400 to CNY 12200,and the proportion of drug cost per capita in the total hospitalization cost decreased from 38.50%to 30.35%.During the five years,the total drug consumption sum of the top 50 drugs ranked by consumption sum showed a decreasing trend(from CNY 21.8046 million to CNY 11.3990 million).Nephropathic drugs,antibacterial drugs,digestive system drugs,cardiovascular system drugs were the main categories of drugs used by inpatients over the years,and the consumption sum of nephropathic drugs was the highest over the years except in 2019(second only to antibacterial drugs).There were fifteen drugs in the top 50 for five consecutive years,including eight categories.During the five years,the total DDDs of the top 50 drugs ranked by DDDs showed a downward trend(from 32.65×10^(4)down to 16.84×10^(4)).The top 3 DDDs in a row were kidney disease drugs,cardiovascular system drugs,and digestive system drugs.There were twenty-one kinds of drugs in the top 50 for five consecutive years,including seven categories.Conclusion Most of the drugs used for inpatients underwent renal dialysis in the hospital are for the main symptoms and common complications of patients,and the rationality of drug use is high.