临床药师参与1例多系统多重耐药鲍曼不动杆菌感染药学监护实践

Clinical Pharmacists′Participation in the Pharmaceutical Care Practice of Multi-System Infection Caused by Multi-Drug-Resistant Acinetobacter Baumannii:A Case Report

目的探讨临床药师在多系统多重耐药鲍曼不动杆菌感染患者抗感染治疗中开展药学监护的价值。方法临床药师参与1例多系统多重耐药鲍曼不动杆菌感染的药学会诊,查看患者病情并结合相关专家共识推荐,建议将抗感染治疗方案由头孢哌酮钠舒巴坦钠+左氧氟沙星+美罗培南(均静脉滴注),调整为头孢哌酮钠舒巴坦钠+舒巴坦+米诺环素(前两药静脉滴注,后药口服)。结果医师采纳建议,患者体温逐渐恢复正常,相关感染指标恢复正常,于入院第42天达到临床治愈标准,续用抗菌药物治疗2周后出院。结论临床药师参与多系统多重耐药细菌的抗感染治疗并进行药学监护,可提高药物治疗水平。

Objective To investigate the role of clinical pharmacists in the pharmaceutical care of the anti-infection treatment of patients with multi-system infection caused by multi-drug-resistant Acinetobacter baumannii.MethodsThe clinical pharmacists participated in the pharmaceutical consultation of a case of multi-system infection caused by multi-drug-resistant Acinetobacter baumannii,and suggested adjusting the anti-infection treatment plan from intravenous drip of cefoperazone sodium and sulbactam sodium+levofloxacin+meropenem to intravenous drip of cefoperazone sodium and sulbactam sodium+sulbactam,and oral administration of minocycline based on the patient’s condition and the relevant experts’consensus and recommendation.ResultsThe doctor adopted the suggestion,and the patient’s temperature gradually returned to normal,as well as the relevant infection indicators.The patient reached the clinical cure standard on the 42nd day of admission,and was discharged after two weeks of continued treatment with antibacterial drugs.ConclusionClinical pharmacists can improve the level of drug therapy by participating in the anti-infection treatment and pharmaceutical care of multi-system infection caused by multi-drug-resistant bacteria.