放线菌及其代谢产物研究进展——基于CiteSpace可视化分析

Actinomycetes and their metabolites:visual analysis based on CiteSpace

【目的】探究放线菌及其代谢产物的研究现状和发展趋势。【方法】本文利用CiteSpace软件对Web of Science数据库中收录的2001‒2021年间与放线菌及其代谢产物研究相关文献进行了可视化分析。【结果】中国在放线菌代谢产物研究领域发文量位居全球第一,发文量最大的研究机构为中国科学院。【结论】该研究领域趋向多学科融合化,主要涉及药理与药剂学、化学等多个学科,目前该研究领域所涉及的学科主要集中于生物化学与分子生物学。而在研究内容方面,研究者多侧重于放线菌代谢产物的生物合成,此外,放线菌种质资源挖掘也成为目前研究者关注的热点内容。

[Objective]To explore the research status and development of actinomycetes and their metabolites.[Methods]We used CiteSpace for a bibliometric review of the literature extracted from Web of Science(WOS)during 2001-2021.[Results]China ranked the first in the world in terms of the number of the published papers involving actinomycete metabolites.Chinese Academy of Sciences had the largest number of published papers in this field among all institutions.[Conclusion]The research of actinomycete metabolites tends to involve multiple disciplines such as pharmacology,pharmacy,chemistry,biochemistry and molecular biology.In terms of the research content,most researchers focus on the biosynthesis of actinomycete metabolites.In addition,the mining of actinomycete germplasm resources has become a hot topic in the field.