小脑性缄默综合征的研究新进展

Advances in research of cerebellar mutism syndrome

小脑性缄默综合征(CMS)常见于儿童后颅窝肿瘤术后,涉及语言、运动、情感和认知的功能损害,临床表现复杂,不同个体的临床表现具有一定的差异,目前尚无确定的临床诊断标准。髓母细胞瘤、肿瘤位于中线是小脑性缄默综合征的独立危险因素,然而性别、年龄是否和其相关仍需要进一步验证。目前尚无有效的措施降低小脑性缄默综合征的发生率。此外,小脑性缄默综合征的全方面康复需要得到关注。建立跨学科的团队合作对于小脑性缄默综合征的研究和康复治疗具有积极意义。

Cerebellar mutism syndrome(CMS)is common in children after posterior cranial fossa tumour surgery,which involves the impairment of language,movement,emotion and cognition.The clinical manifestations are complex.There exist a variety of differences in clinical manifestations among individuals.Medulloblastoma and midline located tumor are independent risk factors for CMS,but whether sex and age are related to CMS needs to be validated furthermore.At present,there is no effective measure to reduce the incidence of CMS.In addition,more attention needs to be paid to the comprehensive rehabilitation of CMS.The establishment of interdisciplinary teamwork is of positive significance for the research and rehabilitation of CMS.