摘要
猪流行性腹泻病毒(Porcine epidemic diarrhea virus,PEDV)是目前引起猪群病毒性腹泻的主要病原之一,给我国乃至世界养猪业造成巨大经济损失。临床上7日龄以内的仔猪发病率最高,病死率可达100%,目前,疫苗仍是预防PEDV的重要手段。本文从流行病学、临床症状与疫苗研究现状等方面分析传统疫苗免疫效果差的原因,阐述PEDV的基本情况及其免疫防控,为新型疫苗研制提供理论参考。
Porcine epidemic diarrhea virus(PEDV)is one of the main pathogens causing viral diarrhea in pigs,causing huge economic losses to the pig industry in my country and even the world. Clinically,piglets within 7 days of age have the highest morbidity rate,and the case fatality rate can reach 100%. At present,vaccines are still an important means of preventing PEDV. This paper analyzes the reasons for the poor immune effect of traditional vaccines from the aspects of epidemiology,clinical symptoms and vaccine research status,and expounds the basic situation of PEDV and its immune prevention and control,so as to provide theoretical reference for the development of new vaccines.
作者
应碧云
朱利塞
向蕊
李祎云
白挨泉
王贵平
贾爱卿
YING Biyun;ZHU Lisai;XIANG Rui;LI Yiyun;BAI aiquan;WANG Guiping;JIA Aiqing(Foshan University,Foshan,Guangdong 528231;Guangdong Haid Institute of Animal Husbandry&Veterinary,Guangzhou,Guangdong 511400;Guangdong Provincial Key Laboratory of Pig Breeding and Pig Disease Prevention and Control Technology Research Enterprise,Guangzhou,Guangdong 511400)
出处
《广东畜牧兽医科技》
2022年第5期35-40,共6页
Guangdong Journal of Animal and Veterinary Science
基金
省级乡村振兴战略专项(200-2018-XMZC-0001-107-0145)
广东省现代农业产业体系生猪创新团队(2021KJ126)
番禺区创新创业领军团队项目(2017-R02-4)
广东省科技计划项目(2020B1212070023)。
关键词
猪流行性腹泻
疫苗
变异
S蛋白
Porcine epidemic diarrhea
Vaccine
Variation
Spike protein
