胺碘酮与西地兰治疗急诊危重症伴快速心律失常的临床效果对比

Clinical effect comparison of amiodarone and cedilanide in the treatment of emergency critical patients with tachyarrhythmia

目的:对比分析胺碘酮与西地兰治疗急诊危重症伴快速心律失常的临床效果。方法:择取2020年1月至2020年12月接诊的72例急诊危重症伴快速心律失常病患,按随机数字法分为两组,参照组36例予以西地兰治疗,观察组36例予以胺碘酮治疗。分析对比组间治疗前后心率、心功能和生活质量改善情况,以及不良反应发生情况。结果:治疗前组间心率、LVEF、LVEDD和E/A值对比差异无统计学意义(P>0.05),治疗后观察组心率较参照组低,LVEF、LVEDD和E/A值等较参照组高;不良反应发生率5.56%较参照组的27.78%低,窦性心律转复率91.67%较参照组的69.44%高(P<0.05)。结论:胺碘酮在急诊危重症伴快速心律失常的治疗中效果比西地兰更好,其有利于促进病患心功能恢复,提升窦性心律转复率,且安全性更高,值得临床首选应用。

Objective:To compare and analyze the clinical effect of amiodarone and cedilanide in the treatment of emergency critical patients with tachyarrhythmia.Methods:72 cases of emergency critical patients with tachyarrhythmia from Januaryr 2020 to December 2020 were randomly divided into control group(36 cases)and observation group(36 cases).The improvement of heart rate,cardiac function and quality of life,as well as the occurrence of adverse reactions were analyzed and compared between the two groups before and after treatment.Results:Before treatment,there was no significant difference in heart rate,LVEF,LVEDd and E/a value between the two groups(P>0.05).After treatment,the heart rate of the observation group was lower than that of the reference group,LVEF,LVEDd and E/a value were higher than that of the reference group;the incidence of adverse reactions was 5.56%lower than 27.78%of the reference group,and the conversion rate of sinus rhythm was 91.67%higher than 69.44%of the reference group(P<0.05).Conclusion:Amiodarone is more effective than cedilanide in the treatment of emergency critical patients with tachyarrhythmia,which is more conducive to promoting the recovery of patients'cardiac function,improving the conversion rate of sinus rhythm,and has higher safety,so it is worthy of clinical application.