摘要
呕吐毒素是对粮谷、饲料原料和饲料等污染最为普遍和严重的真菌毒素之一,畜禽摄入呕吐毒素污染的饲料会出现呕吐、腹泻、拒食和体重减轻等急、慢性的中毒症状,严重的可导致死亡,威胁着畜禽的健康养殖。呕吐毒素的毒理机制和代谢转化是农业和食品领域的研究热点。本文主要从呕吐毒素的细胞毒理机制、生物防治方法和脱毒微生物的筛选研究等方面,综述近年来国内外的研究进展,为防控呕吐毒素对畜禽的危害提供参考。
Deoxynivalenol(DON) is one of the most common and serious polluted mycotoxins that contaminate grains, feed ingredients and feed. The acute or chronic poisoning symptoms of feed-borne exposure to DON in animals are vomiting, diarrhea, feed refusal, weight loss and even death, which seriously threatens the healthy breeding of animal. The toxicity mechanism and metabolic transformation of DON are the research hotspots in the fields of agriculture and food. This article reviews the latest domestic and international research progress in the cytotoxicological mechanism, biological prevention methods and detoxification microorganism screening of DON. It is expected to provide references for prevention and control of the harm of DON to animal.
作者
邓诣群
林如琴
吴思婷
余丹妮
刘思
DENG Yiqun;LIN Ruqin;WU Siting;YU Danni;LIU Si(College of Life Sciences,South China Agricultural University/Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms/Guangdong Laboratory for Lingnan Modern Agriculture/Key Laboratory of Zoonosis of the Ministry of Agriculture and Rural Affairs,Guangzhou 510642,China)
出处
《华南农业大学学报》
CAS
CSCD
北大核心
2022年第6期87-96,共10页
Journal of South China Agricultural University
基金
国家自然科学基金-广东联合基金重点项目(U1901207)
岭南现代农业科学与技术广东省实验室科研项目(NZ2021016)
国家自然科学基金(32102718)。
关键词
呕吐毒素
真菌毒素
毒理
生物防治
脱毒微生物
Deoxynivalenol
Mycotoxin
Toxicology
Biological control
Detoxification microorganism
