新型含吡啶基团二羧酸配体的合成及单晶培养

Synthesis and Single Crystal Growth of Novel Dicarboxylic Acid Ligands Containing Pyridine Group

以1,4-二溴-2,5-二甲基苯和4-吡啶硼酸为原料,经两步反应合成了一种新颖的含吡啶基团的二羧酸配体。通过核磁共振氢谱及傅里叶变换红外光谱对配体结构进行表征,通过热重分析对配体的热稳定性进行了测试;通过溶剂热法对配体的单晶进行培养,并考察反应温度、时间、pH和溶剂等条件对单晶培养的影响。结果表明:在反应温度为80℃,反应时间为12 h、溶剂为蒸馏水、溶液pH=5的条件下可获得高质量单晶。该配体为单斜晶系,属于C 2/c空间群,结构中含有4个氧原子和2个氮原子,可为金属离子的配位提供足够的位点,有望应用于配合物的设计或催化、吸附和医药载体等行业。

A novel dicarboxylic acid ligand containing pyridine group was synthesized from 1,4-dibromo-2,5-dimethylbenzene and 4-pyridine boronic acid by two-step method.The structure of the ligand was characterized by 1 H NMR and FT-IR.The thermal stability of the ligand was tested by thermogravimetric analysis.Then,the single crystal of ligand was grown by solvothermal method,and the effects of reaction temperature,time,pH,solvent on crystallisation were investigated.The results show that high quality single crystals can be obtained under the conditions of reaction temperature of 80℃,reaction time of 12 h,and distilled water as solvent of pH=5.The ligand is monoclinic crystal system,belonging to C 2/c space group.The structure of the ligand contains four oxygen atoms and two nitrogen atoms,which can provide sufficient sites for the coordination of metal ions.It is expected to be applied to the design of complexes or catalysis,adsorption,pharmaceutical carrier and other industries.