七七汤结合心理疏导治疗围绝经期综合征的疗效观察

Effect of Qiqi decoction combined with psychological counseling on perimenopausal syndrome

目的探讨七七汤结合心理疏导治疗围绝经期综合征(PMS)的临床疗效。方法选取120例PMS以失眠、潮热为主要临床表现的患者,按照随机数字表法分为对照组与研究组,各60例。对照组采用优质护理联合甘麦大枣汤(安慰剂)进行治疗,研究组采用七七汤结合心理疏导。比较两组患者临床疗效、治疗前后改良Kupperman评分、更年期生命质量量表(MENQOL)及焦虑自评量表(SAS)。结果研究组患者治疗总有效率达88.33%,明显高于对照组的61.67%,差异具有统计学意义(P<0.05)。与治疗前相比,两组患者Kupperman评分、SAS评分治疗后均显著降低,差异有统计学意义(P<0.05);与对照组相比,研究组患者Kupperman评分、SAS评分下降程度更明显,差异具有统计学意义(P<0.05)。与治疗前相比,两组患者MENQOL评分治疗后降低,差异有统计学意义(P<0.05);与对照组相比,研究组患者MENQOL评分下降程度更显著,差异有统计学意义(P<0.05)。结论七七汤结合心理疏导治疗PMS可显著改善围绝经期女性的临床症状,提升生活质量,改善焦虑状态,值得临床推广与应用。

Objective To investigate the clinical effect of Qiqi decoction combined with psychological counseling in the treatment of perimenopausal syndrome(PMS).Methods 120 PMS patients with insomnia and hot flashes as the main clinical manifestations were selected and divided into control group and study group according to the random number table method,with 60 cases in each group.The control group was treated with high quality nursing combined with Ganmai Dazao decoction(Placebo),while the study group was treated with Qiqi decoction combined with psychological counseling.The clinical efficacy,modified Kupperman score,menopause Quality of Life scale(MENQOL)and self-rating Anxiety Scale(SAS)before and after treatment were compared between the two groups.Results The total effective rate of the study group was 88.33%,significantly higher than that of the control group(61.67%),and the difference was statistically significant(P<0.05).Compared with before treatment,the Kupperman score and SAS score of the two groups were significantly decreased after treatment,and the difffferences were statistically signifificant(P<0.05).Compared with the control group,the Kupperman score and SAS score of the study group decreased more signifificantly,and the differences were statistically signifificant(P<0.05).Compared with before treatment,the MENQOL score of the two groups was decreased after treatment,and the difference was statistically significant(P<0.05).Compared with the control group,the MENQOL score of the study group decreased more significantly,and the difference was statistically significant(P<0.05).Conclusion Qiqi decoction combined with psychological counseling in the treatment of PMS can significantly improve the clinical symptoms of perimenopausal women,improve the quality of life,and improve the anxiety state,which is worthy of clinical promotion and application.