摘要
分化型甲状腺癌(DTC)容易出现复发和转移,除了甲状腺球蛋白(Tg)及其抗体、超声和^(131)I全身显像(WBS),^(18)F-FDG PET/CT在DTC复发或转移诊断和评估中的应用也越来越多,并显示出明显优势。该文主要综述了^(18)F-FDG PET/CT在^(131)I WBS阴性而Tg阳性(^(131)I WBS-/Tg+)时DTC复发或转移灶的定位、评估病灶分化程度、预测预后、指导^(131)I治疗及其在中高危DTC术后再分期和指导治疗决策中的价值。
Differentiated thyroid cancer(DTC)is prone to relapse and metastasize.In addition to thyroglobulin(Tg)and its antibodies,ultrasound and^(131)I whole-body scan(WBS),^(18)F-FDG PET/CT gains more use in the setting of recurrent or metastatic DTC and shows promise.This article mainly reviews the value of ^(18)F-FDG PET/CT in the location of recurrent or metastasized DTC with negative^(131)I WBS but positive Tg(^(131)I WBS-/Tg+),evaluating their differentiation,predicting the prognosis,guiding^(131)I treatment and its value in restaging DTC with moderate and high risk of relapse and guiding treatment decision.
作者
蒋永继
霍艳雷
吕中伟
马超
Jiang Yongji;Huo Yanlei;Lyu Zhongwei;Ma Chao(Department of Nuclear Medicine,Tenth People′s Hospital of Tongji University,Shanghai 200072,China)
出处
《中华核医学与分子影像杂志》
CAS
CSCD
北大核心
2022年第9期559-562,共4页
Chinese Journal of Nuclear Medicine and Molecular Imaging
基金
国家自然科学基金(81771859)。
