原发性肝癌患者腹腔镜肝叶切除术后发生腹腔积液的影响因素分析

Analysis on the Influencing Factors for the Occurrence of Ascites After Laparoscopic Hepatic Lobectomy in Patients with Primary Liver Cancer

目的分析原发性肝癌患者腹腔镜肝叶切除术后发生腹腔积液的相关影响因素。方法回顾性分析2018年10月至2021年2月在我院行腹腔镜肝叶切除术治疗的86例原发性肝癌患者的临床资料,将术后发生腹腔积液的43例患者纳入发生组,未发生腹腔积液的43例患者纳入未发生组,经单因素和多因素分析探讨原发性肝癌患者腹腔镜肝叶切除术后发生腹腔积液的影响因素。结果发生组的术前Child-Pugh分级B级占比高于未发生组,手术时间长于未发生组(P<0.05)。Logistic回归分析显示,术前Child-Pugh分级B级、手术时间长是原发性肝癌患者腹腔镜肝叶切除术后发生腹腔积液的危险因素(OR>1,P<0.05)。结论Child-Pugh分级B级、手术时间长为原发性肝癌患者腹腔镜肝叶切除术后发生腹腔积液的危险因素,临床可据此实施针对性干预方案,以减少腹腔积液的发生。

Objective To analyze the related influencing factors for the occurrence of ascites after laparoscopic hepatic lobectomy in patients with primary liver cancer.Methods The clinical data of 86 patients with primary liver cancer who underwent laparoscopic hepatic lobectomy in our hospital from October 2018 to February 2021 were retrospectively analyzed.43 patients with ascites after surgery were selected as the occurrence group,and 43 patients without ascites after surgery were selected as the non-occurrence group.Univariate analysis and multivariate analysis were used to explore the influencing factors for the occurrence of ascites after laparoscopic hepatic lobectomy in patients with primary liver cancer.Results The proportion of preoperative Child-Pugh grade B in the occurrence group was higher than that in the non-occurrence group,and the operation time was longer than that in the non-occurrence group(P<0.05).Logistic regression analysis showed that preoperative Child-Pugh grade B and long operation time were the risk factors for the occurrence of ascites after laparoscopic hepatic lobectomy in patients with primary liver cancer(OR>1,P<0.05).Conclusions Child-Pugh grade B and long operation time are the risk factors for the occurrence of ascites after laparoscopic hepatic lobectomy in patients with primary liver cancer.Targeted intervention programs can be implemented in clinic to reduce the occurrence of ascites.