益肾解毒法治疗慢性肾脏病机制研究进展

Research progress on the mechanism of treating chronic kidney disease by invigorating the kidney and removing toxic

慢性肾脏病是各种肾脏病的总称,有病程长、早期难以发现等特点,是当今亟待解决的社会性疾病之一,其发病机制和治疗一直是研究的热点和难点,研究表明中医药是延缓慢性肾脏病进展的有效措施。根据国家级名中医临床经验,慢性肾脏病可依据其“肾虚为本、毒邪为标”的病机,采用益肾解毒法治疗。基于上述背景,本文概述了现代研究中益肾解毒类中药汤剂从多机制、多通路等延缓慢性肾脏病的研究进展。

Chronic kidney disease is a general term for various types of renal diseases characterized by a long course of dis⁃ease and difficulty in early detection.It is one of the social diseases that need to be solved urgently and its pathogenesis and treat⁃ment have always been a hotspot for researchers.Studies have shown that traditional Chinese medicine(TCM)can effectively de⁃lay the progress of chronic kidney disease.According to the clinical experience of national famous TCM physicians,based on its pathogenesis of"kidney deficiency as the foundation and poison as the target",chronic kidney disease can be treated by invigorating the kidney and removing toxic.Based on the above background,this paper summarizes the research progress of invigorating the kidney and removing toxic in delaying chronic kidney disease from multiple mechanisms and pathways in modern research.