益宫颗粒联合缩宫素在剖宫产术后子宫复旧不全患者中的应用效果

The Application Effect of Yigong Granule combined with Oxytocin in Patients with Uterine Involution After Cesarean Section

目的分析不同治疗方案在剖宫产术后子宫复旧不全患者中的应用价值。方法选取平原县第一人民医院于2018年1月~2020年12月收治的100例剖宫产术后子宫复旧不全患者,根据治疗方法分为观察组(采取益宫颗粒联合缩宫素治疗,50例)和对照组(采取缩宫素治疗,50例)。比较两组患者临床疗效、不良反应发生率以及用药1周后每日泌乳量、平均恶露量、腰腹痛消失时间等指标,比较两组患者治疗前后激素水平的变化。结果观察组患者临床疗效明显高于对照组(P<0.05);观察组患者用药1周后每日泌乳量明显高于对照组(P<0.05),平均恶露量、腰腹痛消失时间等指标均低于对照组(P<0.05);两组药物不良反应发生率比较,差异无统计学意义(P>0.05);观察组治疗后促卵泡生成素、促黄体生成素、雌二醇水平均高于对照组(P<0.05),孕酮水平低于对照组(P<0.05)。结论益宫颗粒联合缩宫素有助于加速子宫复旧,缓解恶露、腰腹痛症状,同时有助于提高产妇的泌乳量,且不会增加药物不良反应,值得应用。

Objective To analyze the application of Yigong granule combined with oxytocin in the treatment of patients with uterine involution after cesarean section and its effect on lactation.Methods The clinical data of 100 patients with uterine involution after cesarean section who were admitted to the First People’s Hospital of Pingyuan County from January 2018 to December 2020 were selected for retrospective analysis,and divided into observation group(using Yigong Granule combined with oxytocin treatment,a total of 50 cases)and the control group(with oxytocin treatment,a total of 50 cases).The clinical efficacy,incidence of adverse reactions,daily milk production,average lochia volume,and disappearance time of low back and abdominal pain were compared between the two groups after one week of treatment.Finally,the changes in hormone levels before and after treatment were compared between the two groups.Results The clinical efficacy of the observation group was significantly higher than that of the control group(P<0.05);the daily lactation amount of the observation group was significantly higher than that of the control group after 1 week of medication(P<0.05),and the average amount of lochia,waist and abdominal pain disappeared time and other indicators were lower than those in the control group(P<0.05);there was no statistical significant difference in the adverse drug reaction incidence rate between the two groups(P>0.05);the diff erences in follicle-stimulating hormone,luteinizing hormone,estradiol,and progesterone between the two groups before treatment No significance(P>0.05),follicle-stimulating hormone,luteinizing hormone and estradiol in the observation group were higher than those in the control group(P<0.05),and progesterone was lower than that in the control group(P<0.05).Conclusion Yigong granule combined with oxytocin has a high curative effect,which helps to accelerate the involution of the uterus,relieve the symptoms of lochia and low back and abdominal pain,and at the same time helps to increase the milk production of the puerpera without increasing the adverse drug reactions.It is worthy of popularization and application.