BiPAP呼吸机治疗重症支气管哮喘对患者各项指标的改善探讨

Improvement of Various Indexes in Patients with Severe Bronchial Asthma Treated with BiPAP Ventilator

目的:评估重症支气管哮喘患者实施BiPAP呼吸机治疗的临床效果。方法:选择2019年1月~2020年1月70例本院诊治的重症支气管哮喘患者纳入实验资料,以随机数字表法对患者分成参照组与实验组,每组各35例。分别行常规药物治疗、BiPAP呼吸机治疗,比对两组治疗前后血气指标、肺功能指标、氧化应激指标及生活质量情况。结果:①重症支气管哮喘患者治疗前血气指标未具备明显的组间差异性(P>0.05)。实验组重症支气管哮喘患者治疗后血氧分压高于参照组,较之参照组,实验组治疗后二氧化碳分压较低,数据具有统计学意义(P<0.05);②重症支气管哮喘患者治疗前肺功能指标具有一致性,数据无统计学意义(P>0.05);③重症支气管哮喘患者治疗前后氧化应激指标无组间统计学差异性(P>0.05),实验组重症支气管哮喘患者对比参照组患者治疗后超氧化物歧化酶、谷胱甘肽过氧化物酶较高、脂质过氧化物统计指标较低,具备组间统计学差异性(P<0.05);④实验组重症支气管哮喘患者(94.29%)对比参照组患者(77.14%)总生活质量统计指标较高,具备组间统计学差异性(P<0.05)。结论:重症支气管哮喘患者行BiPAP呼吸机治疗效果显著,可有效改善患者的血气指标与肺功能指标,能够调节患者的氧化应激指标,患者的生活质量水平得以提升。

Objective:To study and compare the clinical efficacy of minimally invasive percutaneous nephroscopy and large channel percutaneous nephroscopy in the treatment of renal calculi.Methods:A total of 66 patients with renal calculi from March 2019 to March 2020 were selected and divided into reference group(33 cases,large channel percutaneous nephroscopy)and observation group(33 cases,minimally invasive percutaneous nephroscopy).The clinical effects of different treatment methods in the two groups were analyzed.Results:①There was no significant difference between groups in blood gas indexes before treatment in patients with severe bronchial asthma(P>0.05).The partial pressure of blood oxygen in the patients with severe bronchial asthma after treatment in the experimental group was higher than that in the reference group.Compared with the reference group,the partial pressure of carbon dioxide in the experimental group after treatment was lower,and the data was statistically significant(P<0.05);②Pulmonary function indexes of patients with severe bronchial asthma before treatment were consistent,and the data were not statistically significant(P>0.05);③There was no statistical difference in oxidative stress indexes between the groups before and after treatment in patients with severe bronchial asthma(P>0.05).Higher and lower statistical indexes of lipid peroxides,with statistical difference between groups(P<0.05);④The patients with severe bronchial asthma in the experimental group(94.29%)compared with the patients in the reference group(77.14%)had higher statistical indicators of total quality of life,and there was a statistical difference between the groups(P<0.05).Conclusion:BiPAP ventilator can effectively improve the blood gas index and pulmonary function index of patients with severe bronchial asthma,regulate the oxidative stress index of patients,and improve the quality of life of patients.