柏栀散联合自拟解毒消肿方治疗火毒蕴结型急性肛痈的临床观察

Clinical Observation of Bozhi Powder Combined with Self-made Jiedu Xiaozhong Decoction in Treating Accumulated Fire-Toxin Syndrome of Acute Perianal Abscess

目的观察柏栀散联合自拟解毒消肿方治疗火毒蕴结型急性肛痈患者的临床疗效。方法将120例火毒蕴结型肛痈患者随机分为试验组与对照组各60例。试验组予柏栀散外敷联合自拟解毒消肿方口服,对照组予头孢地尼胶囊联合甲硝唑片口服,连续治疗5 d,观察两组疗效。结果试验组总有效率为89.66%,高于对照组的60.71%(P<0.05)。试验组中无效患者6例转手术治疗;对照组中无效患者22例转手术治疗。治疗后试验组证候及体征总积分明显低于对照组(P<0.05)。治疗后试验组疼痛指数评分、肿块范围优于对照组,且试验组自行溃透率46.55%高于对照组的19.64%,需切开排脓率18.97%低于对照组的44.64%;试验组主要证候消失时间短于对照组(P<0.05)。结论柏栀散联合自拟解毒消肿方治疗火毒蕴结型肛痈患者临床效果显著。

Objective:To observe the clinical efficacy of Bozhi Powder combined with self-made Jiedu Xiaozhong Decoction in treating accumulated fire-toxin syndrome of acute perianal abscess.Methods:According to inclusion criteria,120 patients with accumulated fire-toxin syndrome of perianal abscess were randomly divided into test group(60 cases)and control group(60 cases).The test group was treated with the external application with Bozhi Powder and oral medication of self-made Jiedu Xiaozhong Decoction.The control group was treated with Cefdinir Capsules and metronidazole tablets.After 5 days of treatment,clinical efficacy was observed.Results:The total effective rate in the test group(89.66%)was significantly higher than that of control group(60.71%)(P<0.05).6 invalid cases in the test group and 22 invalid cases in the control group were transferred for surgical treatment.Before treatment,clinical syndrome and sign scores between groups showed no statistically significant difference(P>0.05).After treatment,clinical syndrome and sign scores in the test group were significantly lower than those of control group(P<0.05).After treatment,the pain scores and abscess areas in the test group were better than those of control group.The natural penetrating rate in the test group(46.55%)was higher than that of control group(19.64%).The ratio of cutting the abscess in the test group(18.97%)was lower than that of control group(44.64%).The disappearance time of major syndromes in the test group was shorter than that of control group(P<0.05).Conclusion:Bozhi Powder combined with self-made Jiedu Xiaozhong Decoction is proven to be effective and safe.The conservative TCM therapy offers the patients with more treatment schemes,reduces the usage rate of the antibiotics and provides references on the control of DDD(defined daily dose)of the antibiotics.It is worthy of clinical promotion.