单光子发射型电子计算机断层扫描设备的研究进展

Research progress of SPECT devices

单光子发射型电子计算机断层扫描(SPECT)是核医学成像的重要手段之一,具有高灵敏度、高特异性、可定量等特点,可用于多种疾病的诊断和药物研究,为肿瘤等重大疾病的早期诊断和精准治疗提供重要依据,在医学成像领域具有独特的优势。SPECT成像设备的主要性能指标是灵敏度和空间分辨率,随着核医学的推广应用,SPECT设备的相关研究发展迅速,在准直器、晶体与探测器和多模态与器官专用成像等方面出现新技术和先进设备,旨在增强SPECT系统的灵敏度,提高空间分辨率,降低信噪比,获得更多图片信息和更清晰的成像效果,推动临床医学的发展。通过综述SPECT设备研究进展,展望其未来发展方向。

Single photon emission computed tomography(SPECT) is one of the most important methods of nuclear medical imaging. It has the characteristics of high sensitivity, high specificity and quantifiable, which can be used in the diagnosis of many diseases and drug research, and it can provide important basis for the early diagnosis and precise treatment of tumor and other serious disease. It has unique advantage in the fields of medical imaging. The main performance indicators of SPECT imaging device included sensitivity and spatial resolution. In recent years, the correlational research of SPECT device developed rapidly with the popularization and application of nuclear medicine,and the new technique and advanced equipment had occurred in some aspects included collimators, crystals and detectors, multi-modality and organ-specific imaging, etc., which aim at strengthening the sensitivity of SPECT system,increasing the spatial resolution, reducing signal to noise ratio(SNR), obtaining more picture information and more clear imaging effect, so as to promote the development of clinical medicine. This paper prospected the future direction of development of SPECT device through summarized the research and development of that.