阿司匹林联合阿托伐他汀钙治疗高血压合并动脉粥样硬化的疗效

Effect of Aspirin Combined With Atorvastatin Calcium on Hypertension Combined With Carotid Atherosclerosis

目的探究高血压合并颈动脉粥样硬化治疗中,阿司匹林联合阿托伐他汀钙的用药治疗效果。方法将宁夏宝石花医院2020年1月—2021年12月收治的106例高血压合并动脉粥样硬化患者作为研究对象,根据不同治疗方法,将患者分为对照组(行阿司匹林治疗)与研究组(行阿司匹林联合阿托伐他汀钙治疗)各53例,比较两组患者治疗效果、血压及血脂改善情况。结果研究组治疗有效率为96.23%,观察组治疗有效率为81.13%,差异有统计学意义(P<0.05)。经治疗后两组患者颈动脉狭窄程度明显降低,差异有统计学意义(P<0.05),其中,研究组颈动脉狭窄程度的改善幅度明显大于对照组,差异有统计学意义(P<0.05)。经治疗后两组患者血脂、血压评价指标均改善明显,差异有统计学意义(P<0.05),但研究组治疗后的血脂、血压指标更优于对照组,差异有统计学意义(P<0.05)。结论在高血压合并粥样动脉硬化治疗中,阿司匹林联合阿托伐他汀钙治疗的效果显著,可有效改善血脂、血压及颈动脉狭窄程度情况,值得推广应用。

Objective To explore the therapeutic effect of aspirin combined with atorvastatin in the treatment of hypertension complicated with atherosclerosis.Methods A total of 106 treated in Ningxia GEM Flower Hospital from January 2020 to December 2021were taken as the research object.According to different treatment methods,the patients were divided into the control group(treated with aspirin)and the study group(treated with aspirin combined with atorvastatin)with 53 cases in each group.The treatment effect,blood pressure and blood lipid improvement of the two groups were compared.Results The effective treatment rate was 96.23%in the study group and 81.13%in the observation group,with significant statistical difference(P<0.05).After treatment,the degree of carotid stenosis in the two groups decreased significantly,with significant statistical differences(P<0.05),and the improvement of the degree of carotid stenosis in the study group was significantly greater than that in the control group,with significant statistical differences(P<0.05).After treatment,the evaluation indexes of blood lipid and blood pressure in the two groups were significantly improved,with significant statistical differences(P<0.05),but the indexes of blood lipid and blood pressure in the study group were better than those in the control group,with significant statistical differences(P<0.05).Conclusion In the treatment of hypertension complicated with atherosclerosis,aspirin combined with atorvastatin has a significant effect,which can effectively improve blood lipid,blood pressure and the degree of carotid stenosis.It is worthy of popularization and application.