自动腹膜透析技术治疗慢性肾脏病的临床效果研究

Study on the clinical effect of automated peritoneal dialysis technology in the treatment of chronic kidney disease

目的分析自动腹膜透析技术在慢性肾脏病(chronic kidney disease,CKD)患者中的应用效果。方法选取2019年1月—2020年1月住院治疗的80例慢性肾脏病患者为研究对象,按照随机数字表分为研究组(40例)和对照组(40例),对照组患者给予持续非卧床腹膜透析治疗,研究组患者给予自动腹膜透析治疗,比较两组患者治疗效果和并发症情况。结果治疗后,两组患者BUN、SCr、血钾及血磷水平均有所降低,其中研究组各项指标明显低于对照组(P<0.05);治疗后,两组患者CD3^(+)、CD4^(+)水平均有所提高,NK细胞水平均有下降,其中研究组CD3^(+)、CD4^(+)水平明显高于对照组,NK细胞水平明显低于对照组(P<0.05);研究组并发症发生率为10.0%,明显低于对照组的35.0%(P<0.01);研究组舒适度明显高于对照组(P<0.001)。结论自动腹膜透析可有效清除慢性肾脏病患者体内毒素,改善机体功能,提高免疫力,提升治疗舒适度,临床效果显著,值得推广应用。

Objective To investigate the application effect of automated peritoneal dialysis technology in the clinical treatment of patients with chronic kidney disease(CKD).Methods 80 patients with chronic kidney disease admitted into People's Hospital of Xingguo County from January 2019 to January 2020 were selected and then divided into study group(40 cases)and control group(40 cases)according to random number table.Patients in the control group were treated with continuous ambulatory peritoneal dialysis while the patients in the study group were given automated peritoneal dialysis.Therapeutic effects and complications were compared between the two groups.Results After treatment,the levels of BUN,SCr,blood potassium and blood phosphorus in both groups were decreased,and all the indexes in the study group were significantly lower than those in the control group(P<0.05);the levels of CD3^(+)and CD4^(+)in both groups increased,while the levels of NK cells decreased,in which the CD3^(+)and CD4^(+)levels in the study group were significantly higher than those in the control group,and the NK cells were significantly lower than those in the control group(P<0.05).The incidence of complications in the study group was 10.0%,which was significantly lower than that in the control group(35.0%)(P<0.05);the comfort level of the study group was significantly higher than that of the control group(P<0.001).Conclusion Automated peritoneal dialysis can effectively remove toxins in patients with chronic kidney disease,and improve body function,immunity and treatment comfort,which is worthy of clinical application and promotion.