脑小血管病工作记忆相关神经认知机制的研究进展

Research progress of neurocognitive mechanisms related to working memory in cerebral small vessel disease

脑小血管病(cerebral small vessel disease,CSVD)是一组以颅内小动脉、小静脉、微动脉、微静脉及毛细血管病变引起的综合征,临床表现以认知障碍、步态异常和情绪障碍等为主[1]。根据国际神经影像学血管性改变标准化报道(standards for reporting vascular changes on neuroimaging,STRIVE)共识[2],CSVD影像标志物为脑白质高信号扩大的血管周围间隙。