稳定期COPD合并肺癌患者吸入药物使用依从性现状及影响因素分析

Analysis of the current status and influencing factors ofinhaled drug use compliance in patients with stable COPD combined with lung cancer

目的调查肺癌合并稳定期COPD患者吸入药物使用依从性现状及影响因素。方法对2019年9月至2021年9月就诊于我院的140例原发性肺癌合并稳定期COPD患者进行问卷调查。分析肺癌合并稳定期COPD患者使用吸入药物依从性情况及其影响因素。结果140例肺癌合并稳定期COPD患者中,37例(26.43%)依从性较好,48例(34.29%)依从性差,55例(39.29%)从来没有使用过吸入药物。对140例肺癌合并稳定期COPD患者进行单因素和多因素Logistic分析显示,人均月收入、自我感觉药效差拒绝使用、担心用药的副作用、吸入药物费用高不报销是影响患者吸入药物治疗依从性的重要危险因素。结论1.仅有26.43%肺癌合并稳定期COPD患者使用吸入药物依从性较好。2.人均月收入、自我感觉药效差拒绝使用、担心用药的副作用、吸入药物费用高不报销是影响肺癌合并稳定期COPD患者吸入药物治疗依从性的重要危险因素。

Objective To investigate the current status and influencing factors of inhaled drug use compliance in patients with lung cancer and stable chronic obstructive pulmonary disease(COPD).Methods A questionnaire was conducted on 140 patients with primary lung cancer complicated with stable COPD who visited our hospital from September 2019 to September 2021.To analyze the compliance of inhaled drugs and their influencing factors in patients with lung cancer complicated with stable COPD.Results Among the 140 patients with lung cancer and stable COPD,37 cases(26.43%)had good compliance,48 cases(34.29%)had poor compliance,and 55 cases(39.29%)had never used inhaled drugs.Univariate and multivariate logistic analysis of 140 patients with lung cancer and stable COPD showed that per capita monthly income,poor efficacy,fear of side effects,and high cost of inhaled drugs were important risk factors affecting patients′compliance with inhaled drugs.Conclusion 1.Only 26.43%of lung cancer patients with stable COPD had good compliance with inhaled drugs.2.Monthly income per capita,self-perception of poor efficacy,refusal to use,worrying about the side effects of medication,and high cost of inhaled drugs and non-reimbursement are important risk factors affecting the compliance of inhaled drugs therapy in patients with lung cancer and stable COPD.