基于数据挖掘探讨针灸治疗重症肌无力的选穴规律

Exploration of Acupoint Rules in Acupuncture and Moxibustion Treatment of Myasthenia Gravis Based on Data Mining

目的:通过对临床上针灸治疗重症肌无力的选穴规律和方法进行数据挖掘,为针灸治疗重症肌无力提供科学依据。方法:检索国家知识基础设施数据库(CNKI)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、中国生物医学文献数据库(CBM)及PUBMED中的临床研究文献,筛选出符合标准的针灸治疗重症肌无力的文献,使用数据挖掘技术分析其选穴规律。结果:纳入65篇文献,涉及腧穴共128个,使用总频次780次。其选用腧穴中,以足三里为多,其次排名依次为阳白、攒竹、三阴交、合谷;选用的腧穴归经以足太阳膀胱经为最,足阳明胃经及足少阳胆经较为常用;特定穴以合穴、下合穴及背俞穴选用频次高;关联规则分析中,阳白与足三里、丝竹空、足三里与阳白在穴位配伍上最为常见;聚类分析中,足三里,阳白与攒竹,三阴交与合谷最为常见。结论:针灸治疗重症肌无力选穴具有一定规律和相似性,其规律可为临床选穴提供参考意义。

Objective:To conduct data mining on the acupoint rules and methods in clinical acupuncture and moxibustion treatment of myasthenia gravis.Methods:China National Knowledge Infrastructure(CNKI),VIP,Wanfang Data,Chinese Biomedical Literature Database(CBM)and PubMed were retrieved to screen articles on acupuncture and moxibustion treatment of muscular gravis according to the screening conditions,and the acupoint selection rules were analyzed by data mining.Results:A total of 65 articles were included,involving 128 acupoints,with a total frequency of 780.Among the selected acupoints,Zusanli(ST 36)was the most,followed by Yangbai(GB 14),Cuanzhu(BL 2),Sanyinjiao(SP 6),and Hegu(LI 4).The selected acupoints mostly acted on foot greater yang bladder meridian(BL),and foot yang brightness stomach meridian(ST)and foot lesser yang gallbladder meridian(GB)were commonly used.In terms of specific points,sea point,lower sea point and back transport point were selected with high frequency.The association rule analysis indicated Yangbai&Zusanli and Sizhukong&Zusanli&Yangbai were the most common acupoint combination.Cluster analysis demonstrated Zusanli,Yangbai&Cuanzhu,and Sanyinjiao&Hegu were the most common.Conclusion:There were certain rules and similarities in the selection of acupoints in acupuncture and moxibustion treatment of myasthenia gravis,and the rules could provide reference for clinical acupoint selection.